Magdalena Winiarska

TL;DR: Since PpIX is a potent photosensitizer this metabolic pathway can be exploited in photodynamic therapy (PDT), this is an already approved therapeutic strategy making ALA one of the most successful prodrugs used in cancer treatment.

TL;DR: It is indicated that bortezomib treatment leads to left ventricular contractile dysfunction manifested by a significant drop in left ventricle ejection fraction.

TL;DR: Statins were shown to interfere with both detection of CD20 and antilymphoma activity of rituximab, which has significant clinical implications, as impaired binding of mAbs to conformational epitopes ofCD20 elicited by statins could delay diagnosis, postpone effective treatment, or impair anti-lymphomaactivity of r ituximabs.

TL;DR: Melphalan administration in vivo could stimulate a CD8(+) T cell-dependent protective antitumor response and was potentiated in combination with exogenous calreticulin, but not tumor necrosis factor, a cytokine often combined with Mel-ILP.

TL;DR: Inhibition of HO-1 exerts antitumor effects but should not be used to potentiate antitumors effects of cancer chemotherapeutics unless procedures of selective tumor targeting of HO -1 inhibitors are developed.