M
Manabu Futamura
Researcher at Gifu University
Publications - 82
Citations - 1215
Manabu Futamura is an academic researcher from Gifu University. The author has contributed to research in topics: Breast cancer & Cancer. The author has an hindex of 16, co-authored 82 publications receiving 856 citations.
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Journal ArticleDOI
Spread of colorectal cancer micrometastases in regional lymph nodes by reverse transcriptase-polymerase chain reactions for carcinoembryonic antigen and cytokeratin 20
Manabu Futamura,Yukihiro Takagi,Hisashi Koumura,H Kida,Hiromi Tanemura,Kuniyasu Shimokawa,Shigetoyo Saji +6 more
TL;DR: To assess the risk of recurrence and accurately determine the spread of tumor cells, lymph node micrometastases in a series of colorectal cancer patients were examined.
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M1 Macrophage and M1/M2 ratio defined by transcriptomic signatures resemble only part of their conventional clinical characteristics in breast cancer.
Masanori Oshi,Masanori Oshi,Yoshihisa Tokumaru,Yoshihisa Tokumaru,Mariko Asaoka,Mariko Asaoka,Li Yan,Vikas Satyananda,Ryusei Matsuyama,Nobuhisa Matsuhashi,Manabu Futamura,Takashi Ishikawa,Kazuhiro Yoshida,Itaru Endo,Kazuaki Takabe +14 more
TL;DR: “M1” high tumors were associated with aggressive cancer biology and favorable tumor immune microenvironment but not with survival benefit, which resembled only part of their conventional clinical characteristics.
Journal Article
KRAS signaling enriched triple negative breast cancer is associated with favorable tumor immune microenvironment and better survival.
Yoshihisa Tokumaru,Yoshihisa Tokumaru,Masanori Oshi,Eriko Katsuta,Li Yan,Vikas Satyananda,Nobuhisa Matsuhashi,Manabu Futamura,Yukihiro Akao,Kazuhiro Yoshida,Kazuaki Takabe +10 more
TL;DR: It is found that patients with enrichment of KRAS signaling gene sets were associated with inflammation and favorable tumor immune microenvironment as well as improved survival in TNBC.
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MiR-133b inhibits growth of human gastric cancer cells by silencing pyruvate kinase muscle-splicer polypyrimidine tract-binding protein 1.
Taro Sugiyama,Kohei Taniguchi,Nobuhisa Matsuhashi,Toshihiro Tajirika,Manabu Futamura,Tomoaki Takai,Yukihiro Akao,Kazuhiro Yoshida +7 more
TL;DR: Findings indicated that miR‐133b acted as a tumor‐suppressor through negative regulation of the Warburg effect in gastric cancer cells.
Journal ArticleDOI
PTBP1-associated microRNA-1 and -133b suppress the Warburg effect in colorectal tumors.
Kohei Taniguchi,Miku Sakai,Nobuhiko Sugito,Minami Kumazaki,Haruka Shinohara,Nami Yamada,Tatsushi Nakayama,Hiroshi Ueda,Yoshihito Nakagawa,Yuko Ito,Manabu Futamura,Bunji Uno,Yoshinori Otsuki,Kazuhiro Yoshida,Kazuhisa Uchiyama,Yukihiro Akao +15 more
TL;DR: The results suggested that PTBP1 andPTBP1-associated miR-1 and -133b are crucial molecules for the maintenance of the Warburg effect in colorectal tumors.