M
Manjula Thimma
Researcher at King Abdullah University of Science and Technology
Publications - 13
Citations - 2018
Manjula Thimma is an academic researcher from King Abdullah University of Science and Technology. The author has contributed to research in topics: Chromatin & Genome. The author has an hindex of 7, co-authored 11 publications receiving 1792 citations. Previous affiliations of Manjula Thimma include Hammersmith Hospital & Imperial College London.
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Journal ArticleDOI
InterPro: the integrative protein signature database
Sarah Hunter,Rolf Apweiler,Teresa K. Attwood,Amos Marc Bairoch,Alex Bateman,David Binns,Peer Bork,Ujjwal Das,Louise C. Daugherty,Lauranne Duquenne,Robert D. Finn,Julian Gough,Daniel H. Haft,Nicolas Hulo,Daniel Kahn,Elizabeth Kelly,Aurélie Laugraud,Ivica Letunic,David M. Lonsdale,Rodrigo Lopez,Martin Madera,John Maslen,Craig McAnulla,Jennifer McDowall,Jaina Mistry,Alex L. Mitchell,Nicola Mulder,Darren A. Natale,Christine A. Orengo,Antony F. Quinn,Jeremy D. Selengut,Christian J. A. Sigrist,Manjula Thimma,Paul Thomas,Franck Valentin,Derek Wilson,Cathy H. Wu,Corin Yeats +37 more
TL;DR: The InterPro database integrates together predictive models or ‘signatures’ representing protein domains, families and functional sites from multiple, diverse source databases: Gene3D, PANTHER, Pfam, PIRSF, PRINTS, ProDom, PROSITE, SMART, SUPERFAMILY and TIGRFAMs.
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Genome-wide expression analysis offers new insights into the origin and evolution of Physcomitrella patens stress response.
Basel Khraiwesh,Enas Qudeimat,Manjula Thimma,Amphun Chaiboonchoe,Kenan Jijakli,Amnah Alzahmi,Marc Arnoux,Kourosh Salehi-Ashtiani +7 more
TL;DR: A comprehensive analysis of transcriptome dynamics, defining profiles of elicited gene regulation responses to abiotic stress-associated hormone Abscisic Acid, cold, drought, and salt treatments, revealed genomic delineation concomitant with the evolutionary movement to land, including a general gene family complexity and loss of genes associated with different functional groups.
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eQTL Explorer: integrated mining of combined genetic linkage and expression experiments
Michael Mueller,Anuj Goel,Manjula Thimma,Nicholas J. Dickens,Timothy J. Aitman,Jonathan Mangion +5 more
TL;DR: The eQTL Explorer as discussed by the authors tool stores expression profiles, linkage data and information from external sources in a relational database and enables simultaneous visualization and intuitive interpretation of the combined data via a Java graphical interface.
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Carotenoid metabolic profiling and transcriptome‐genome mining reveal functional equivalence among blue‐pigmented copepods and appendicularia
TL;DR: Molecular evidences for the bioconversion and accumulation of blue astaxanthin–protein complexes underpinning the observed ecological functional equivalence and adaptive convergence among neustonic mesozooplankton are provided.
Journal ArticleDOI
Nuclear AGO1 Regulates Gene Expression by Affecting Chromatin Architecture in Human Cells
Muhammad Shuaib,Krishna Mohan Parsi,Manjula Thimma,Sabir A. Adroub,Hideya Kawaji,Loqmane Seridi,Yanal Ghosheh,Alexandre Fort,Bodor Fallatah,Timothy Ravasi,Piero Carninci,Valerio Orlando +11 more
TL;DR: The data suggest that enhancer-associated AGO1 contributes to the fine-tuning of chromatin architecture and gene expression in human cells.