Showing papers by "Manos Papadakis published in 2022"
TL;DR: In this article , a deep learning framework was proposed for the automated detection of GFAP-immunolabeled astrocytes in brightfield or fluorescent micrographs.
Abstract: Abstract Astrocytes, a subtype of glial cells with a complex morphological structure, are active players in many aspects of the physiology of the central nervous system (CNS). However, due to their highly involved interaction with other cells in the CNS, made possible by their morphological complexity, the precise mechanisms regulating astrocyte function within the CNS are still poorly understood. This knowledge gap is also due to the current limitations of existing quantitative image analysis tools that are unable to detect and analyze images of astrocyte with sufficient accuracy and efficiency. To address this need, we introduce a new deep learning framework for the automated detection of GFAP-immunolabeled astrocytes in brightfield or fluorescent micrographs. A major novelty of our approach is the applications of YOLOv5, a sophisticated deep learning platform designed for object detection, that we customized to derive optimized classification models for the task of astrocyte detection. Extensive numerical experiments using multiple image datasets show that our method performs very competitively against both conventional and state-of-the-art methods, including the case of images where astrocytes are very dense. In the spirit of reproducible research, our numerical code and annotated data are released open source and freely available to the scientific community.
TL;DR: In this article , the authors examined the strategic impact of standards and blockchain technology in the maritime business operations' management, which could be achieved through the prominent from Bitcoin Cryptocurrency Blockchain Technology as a digital verification mechanism complying with global identification, technical and data exchange standards.
Abstract: Modern economy faces one of its’ greatest challenges of all times and disruptive innovations are available to corporations as solutions to major business drawbacks (e.g., traceability, communication, data exchange, information modelling etc.). The Maritime Industry combines multiple supply chain stakeholders and operations, globally, generating critical data and exchanging important documents. Mostly, these are paper-based and proprietary. For this industry, digitally exchanged data, must be unambiguous, semantically aligned between trading partners and shared with resilience in real-time using a common operational language. This could be achieved through the prominent from Bitcoin Cryptocurrency Blockchain Technology as a digital verification mechanism complying with global identification, technical and data exchange standards. Acknowledging the difficulties faced in the Maritime Business Operations’ Management, this paper examines the strategic impact of Standards and Blockchain Technology in the industry’s processes.