Manuela R. Pausan

TL;DR: The archaeome remains mysterious, and many questions with respect to potential pathogenicity, function, and structural interactions with their host and other microorganisms remain.

TL;DR: Conservative protocols based on specifically archaea-targeting, PCR-based methods were established to retrieve first insights into the archaeomes of the human gastrointestinal tract, lung, nose, and skin, and were able to detect unexpectedly high diversity of archaea associated with different body parts.

TL;DR: Compared the different operating, maintenance and monitoring procedures as well as microbial communities therein, the importance to properly understand the effects of confinement on the microbial diversity, the possible risks represented by some of these microorganisms and by the evolution of (antibiotic) resistances in such environments – and the need to reassess the current hygiene standards is emphasized.

TL;DR: This work evaluated methodological set-ups to detect archaea in samples from five different body sites and identified the primer pair combination 344f-1041R/519F-806R which performed superior for the analysis of the archaeome of gastrointestinal tract, oral cavity and skin.

TL;DR: Data indicate that a changed microbial community composition in SCC, specified by S. aureus overabundance, might promote tumor cell growth via modulation of hBD-2 expression.