M
Margaret E. Wierman
Researcher at University of Colorado Denver
Publications - 157
Citations - 8781
Margaret E. Wierman is an academic researcher from University of Colorado Denver. The author has contributed to research in topics: Gonadotropin-releasing hormone & Gonadotropin. The author has an hindex of 46, co-authored 148 publications receiving 7818 citations. Previous affiliations of Margaret E. Wierman include United States Department of Veterans Affairs & Harvard University.
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Journal ArticleDOI
Association of testosterone therapy with mortality, myocardial infarction, and stroke in men with low testosterone levels
Rebecca Vigen,Colin O'Donnell,Anna E. Barón,Gary K. Grunwald,Thomas M. Maddox,Steven M. Bradley,Al Barqawi,Glenn Woning,Margaret E. Wierman,Mary E. Plomondon,John S. Rumsfeld,P. Michael Ho +11 more
TL;DR: Among a cohort of men in the VA health care system who underwent coronary angiography and had a low serum testosterone level, the use of testosterone therapy was associated with increased risk of adverse outcomes, and these findings may inform the discussion about the potential risks ofosterone therapy.
Journal ArticleDOI
Molecular biology of the pituitary gonadotropins.
TL;DR: This review will discuss the structure of the gonadotropin subunits, theructure of the genes that encode them, and the regulation of their secretion and synthesis.
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Somatic and Germ-Line Mutations of the HRPT2 Gene in Sporadic Parathyroid Carcinoma
Trisha M. Shattuck,Stiina Välimäki,Takao Obara,Randall D. Gaz,Orlo H. Clark,Dolores M. Shoback,Margaret E. Wierman,Katsuyoshi Tojo,Christiane M. Robbins,John D. Carpten,Lars-Ove Farnebo,Catharina Larsson,Andrew Arnold +12 more
TL;DR: Sporadic parathyroid carcinomas frequently have HRPT2 mutations that are likely to be of pathogenetic importance, and certain patients with apparently sporadic parathyro carcinoma carry germ-line mutations in HRPT1 and may have the HPT-JT syndrome or a phenotypic variant.
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Challenges to the measurement of estradiol: an endocrine society position statement.
William Rosner,Susan E. Hankinson,Susan E. Hankinson,Patrick M. Sluss,Hubert W. Vesper,Margaret E. Wierman,Margaret E. Wierman +6 more
TL;DR: Although modern immunoassays and liquid chromatography/tandem mass spectrometry-based methods for estradiol are reasonably well suited to the diagnosis and management of infertility, the very low concentrations that appear to be crucial in nonreproductive tissues are a separate and more difficult issue.
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Androgen therapy in women: an Endocrine Society Clinical Practice guideline.
Margaret E. Wierman,Rosemary Basson,Susan R. Davis,Sundeep Khosla,Karen K. Miller,William Rosner,Nanette Santoro +6 more
TL;DR: Although there is evidence for short-term efficacy of testosterone in selected populations, such as surgically menopausal women, the Task Force recommends against the generalized use of testosterone by women because the indications are inadequate and evidence of safety in long-term studies is lacking.