Showing papers by "Maria Auxiliadora Coelho Kaplan published in 2001"
TL;DR: A great number of non-oxygenated monoterpenes and sesquiterpenes are derived from E,E-farnesyl-PP, suggesting a preference of these species to synthesize metabolites from this pathway.
119 citations
TL;DR: Flavonoids have been shown to be good taxonomic markers for Asteraceae and some implications of flavonols, flavones and other types are discussed for tribes and subtribes of Asteraceae.
79 citations
TL;DR: The essential oil from Piper solmsianum leaves and its major compound (sarisan) showed to have exciting and depressant effects in the tested animals.
Abstract: The essential oil from Piper solmsianum leaves and its major compound (sarisan) were tested to verify their influences upon mice behaviour. The essential oil was obtained by hydrodistillation in a modified Clevenger extractor and analysed by GC/ MS. This analysis revealed in the oil the presence of monoterpenes, sesquiterpenes and of arylpropanoids. The compound sarisan, a myristicin analogue, was isolated from the oil to perform the pharmacological tests. Emulsions of the oil and of sarisan (5.0 and 10.0% v/v) were used in the tests. Pentobarbital (30 mg/ kg s.c.) or diazepam (2.5 mg/ kg s.c.) were tested as standard drugs to verify depressant or anxiolytic effects, respectively. Both essential oil and sarisan showed to have exciting and depressant effects in the tested animals.
24 citations
TL;DR: The flavone-flavolol ratio for Dicotyledoneae is studied through graphic comparisons between indices indicative of morphological tendencies: the herbaceousness and Sporne indices that show a tendency toward the reduction of flavone biosynthesis in arboreous and shrubby taxa.
13 citations
12 citations
TL;DR: Compared to the high activities of psoralen and bergapten, dorstenin showed lower genotoxic effect and photosensitizing and mutational properties.
Abstract: Dorstenin, 5-[3-(4,5-dihydro-5,5-dimethyl-4-oxo-2-furanyl)-butoxy]-7H-furo[3, 2-g] (1) benzopyran-7-one, is a psoralen analog recently isolated from Dorstenia species (Moraceae). In order to characterize its biological activity, its photosensitizing and mutational properties were measured in wild-type E. coli and S. cerevisiae and also in strains carrying mutations which affect DNA repair. Compared to the high activities of psoralen and bergapten, dorstenin showed lower genotoxic effect.
7 citations
TL;DR: The dichloromethane fraction obtained from the methanolic extract of leaves of P. lhotzkyanum afforded a C-glucosylflavone (kaplanin) together with sakuranetin, methyl 4-methoxydihydroferulate and a mixture of methyl ferulate and dihydro-ferulate derivatives as mentioned in this paper.
Abstract: The dichloromethane fraction obtained from the methanolic extract of leaves of P. lhotzkyanum afforded a C-glucosylflavone (kaplanin) together with sakuranetin, methyl 4-methoxydihydroferulate and a mixture of methyl ferulate and dihydroferulate derivatives. Spectrometric methods were used to elucidate the structures of these compounds.
7 citations
TL;DR: In this paper, a sesquiterpene alcohol for which spectral data suggested the structure of a 10-aromadendranol was extracted from the leaves of Renealmia chrysotrycha (Zingiberaceae).
Abstract: From the leaves of Renealmia chrysotrycha (Zingiberaceae), we isolated a sesquiterpene alcohol for which spectral data suggested the structure of a 10-aromadendranol. A meticulous NMR investigation, based mainly on vicinal proton-proton coupling constants and NOE interactions, and confirmed by a molecular mechanics calculation, established its relative stereochemistry as that of ledol. This finding resolves several recent literature ambiguities. Three known compounds (aromadendrene, cis-calamenene and palustrol) were also isolated.
3 citations