M
Maria Markaki
Researcher at Foundation for Research & Technology – Hellas
Publications - 41
Citations - 7502
Maria Markaki is an academic researcher from Foundation for Research & Technology – Hellas. The author has contributed to research in topics: Autophagy & Mitophagy. The author has an hindex of 20, co-authored 35 publications receiving 6106 citations. Previous affiliations of Maria Markaki include University of Crete.
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Improvement of lung cancer risk prediction adding SNPs to the HUNT Lung Cancer Model: A HUNT Study.
Oluf Dimitri Røe,Olav Toai Duc Nguyen,Klio Lakiotaki,Ioannis Tsamardinos,Vincenzo Lagani,Maria Markaki +5 more
TL;DR: A novel validated model for risk prediction of lung cancer, the HUNT Lung Cancer Model predicts 6- and 16-year risk of lung cancers with a C-index and AUC of 0.879 and 0.87 respectively.
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Editorial: Mitophagy in physiology and pathology.
TL;DR: This special issue of Mechanism of Ageing and Development presents a series of articles that discuss recent advances and current challenges in the field, which need to be addressed before modulation of mitophagy can be considered for therapeutic intervention.
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Increased levels of microRNA‐320 in blood serum and plasma is associated with imminent and advanced lung cancer
Therese Haugdahl Nøst,Anne Heidi Skogholt,Ilona Urbarova,Robin Mjelle,Erna-Elise Paulsen,Tom Donnem,Sigve Andersen,Maria Markaki,Oluf Dimitri Røe,Mikael Johansson,Mattias Johansson,Bjørn Henning Grønberg,Torkjel M. Sandanger,P. Saetrom +13 more
TL;DR: In this article , the authors identified upregulated candidate miRNAs in plasma specimens from a hospital-based study sample of 128 patients with confirmed lung cancer and 62 individuals with suspected but confirmed negative lung cancer (FalsePos).
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Local coordination of mRNA storage and degradation near mitochondria modulates C. elegans ageing.
TL;DR: In this article , a pivotal role for specific elements of the 5'-3' mRNA degradation pathway in the regulation of mitochondrial abundance and function was uncovered, revealing a multifaceted role of mRNA metabolism in mitochondrial biogenesis.
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Mitophagy and long-term neuronal homeostasis.
TL;DR: In this article , the contribution of mitophagy, a selective form of autophagy that targets dysfunctional or superfluous mitochondria for degradation, in maintaining nervous system homeostasis is discussed.