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Maria Santagati

Researcher at University of Catania

Publications -  94
Citations -  2676

Maria Santagati is an academic researcher from University of Catania. The author has contributed to research in topics: Bicyclic molecule & Streptococcus salivarius. The author has an hindex of 23, co-authored 89 publications receiving 2270 citations. Previous affiliations of Maria Santagati include University of Siena.

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Gut Microbiota and Cancer: From Pathogenesis to Therapy

TL;DR: Novel strategies integrating probiotics, such as LGG, with conventional anti-cancer therapies are strongly encouraged, because of the tight association between gut microbiota and tumorigenesis, as well as Gut microbiota and anti- cancer therapy.
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A variation in 3' UTR of hPTP1B increases specific gene expression and associates with insulin resistance.

TL;DR: The data indicate that the 1484insG allele causes PTP1B overexpression and plays a role in insulin resistance, and individuals carrying the 14 84insG variant might particularly benefit from PTP 1B inhibitors, a promising new tool for treatment of insulin resistance.
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Macrolide Efflux Genes mef(A) and mef(E) Are Carried by Different Genetic Elements in Streptococcus pneumoniae

TL;DR: It is suggested that the distinction between the two genes be maintained in Streptococcus pneumoniae isolates, because of the important different characteristics of the strains carrying mef(A) or me f(E).
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Presence of the ica operon in clinical isolates of Staphylococcus epidermidis and its role in biofilm production.

TL;DR: The results showed that icaRADBC was present in 45% of the isolates included in the study, and that such isolates were significantly more resistant to the main antibiotics tested than were ica-negative isolates, and there was evidence to suggest a correlation when at least two genes (icaAD) were co-transcribed.
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Characterization of a Genetic Element Carrying the Macrolide Efflux Gene mef(A) in Streptococcus pneumoniae

TL;DR: The mef(A) gene from a clinical isolate of Streptococcus pneumoniae exhibiting the M-type resistance to macrolides was found to be part of the 7,244-bp chromosomal element Tn1207.1, which contained 8 open reading frames.