Mariamma M. Thalanany

TL;DR: Transfer of adult patients with severe but potentially reversible respiratory failure, whose Murray score exceeds 3.0 or who have a pH of less than 7.20 on optimum conventional management, to a centre with an ECMO-based management protocol is recommended to significantly improve survival without severe disability.

TL;DR: This randomised controlled trial is to assess whether extracorporeal membrane oxygenation will increase the rate of survival without severe disability by six months post-randomisation, and be cost effective from the viewpoints of the NHS and society, compared to conventional ventilatory support.

TL;DR: Compared with CM, transferring adult patients with severe but potentially reversible respiratory failure to a single centre specialising in the treatment of severe respiratory failure for consideration of ECMO significantly increased survival without severe disability.

TL;DR: 'Access to a befriender facilitator' is neither an effective nor a cost-effective intervention in the support of carers of people with dementia, although there is a suggestion of cost-effectiveness for the care dyad (carer and care recipient).

TL;DR: The BEfriending and Costs of CAring trial aimed to establish whether a structured befriending service improved the quality of life of carers of people with dementia, and at what cost.