M
Marie-Cécile Ploy
Researcher at French Institute of Health and Medical Research
Publications - 40
Citations - 1300
Marie-Cécile Ploy is an academic researcher from French Institute of Health and Medical Research. The author has contributed to research in topics: Integron & Gene cassette. The author has an hindex of 17, co-authored 40 publications receiving 1021 citations. Previous affiliations of Marie-Cécile Ploy include University of Limoges.
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Journal ArticleDOI
Integron Involvement in Environmental Spread of Antibiotic Resistance
Thibault Stalder,Olivier Barraud,Olivier Barraud,Magali Casellas,Christophe Dagot,Marie-Cécile Ploy,Marie-Cécile Ploy +6 more
TL;DR: The aim of this review is to provide an in-depth analysis of recent studies of antibiotic-resistance integrons in the environment, highlighting their potential involvement in antibiotic-Resistance outside the clinical context and the impact of human activities.
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Quantitative multiplex real-time PCR for detecting class 1, 2 and 3 integrons
TL;DR: A rapid, quantitative, specific and sensitive Taqman probe-based real-time PCR method with three different primer-probe pairs for simultaneous detection of the three main classes of integron that could prove useful for initial screening of Gram-negative isolates, or clinical samples, for likely multidrug resistance.
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The SOS response promotes qnrB quinolone-resistance determinant expression
Sandra Da Re,Sandra Da Re,Fabien Garnier,Emilie Guerin,Emilie Guerin,Susana Campoy,F. Denis,F. Denis,Marie-Cécile Ploy,Marie-Cécile Ploy +9 more
TL;DR: It is shown that qnrB2 expression is regulated through the SOS response in a LexA/RecA‐dependent manner, and that it can be induced by the quinolone ciprofloxacin, a known inducer of the SOS system.
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Invasive pneumococcal disease incidence in children and adults in France during the pneumococcal conjugate vaccine era: an interrupted time-series analysis of data from a 17-year national prospective surveillance study
Naim Ouldali,Emmanuelle Varon,Corinne Levy,François Angoulvant,François Angoulvant,Scarlett Georges,Marie-Cécile Ploy,Marie Kempf,Julie Cremniter,Robert M. Cohen,Daniel Levy Bruhl,Kostas Danis +11 more
TL;DR: A rebound in cases among children and adults since 2015, driven by several emerging non-PCV13 serotypes, jeopardises the long-term PCV benefits and should be considered in the development of next-generation PCVs.
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Diversity of Class 1 Integron Gene Cassette Rearrangements Selected under Antibiotic Pressure
TL;DR: The results suggest that gene cassette rearrangements via excision are probably less cost-effective than excision and integration of a distal gene cassette closer to Pc, thus leading to higher-level resistance.