Co-Planar Stereotaxic Atlas of the Human Brain—3-Dimensional Proportional System: An Approach to Cerebral Imaging, J. Talairach, P. Tournoux. Georg Thieme Verlag, New York (1988), 122 pp., 130 figs. DM 268

Robert Baan a, Yann Grosse a, Beatrice Lauby-Secretan a, Fatiha El Ghissassi a, Veronique Bouvard a, Lamia Benbrahim-Tallaa a, Neela Guha a, Farhad Islami a, Laurent Galichet a, Kurt Straif a, on behalf of the WHO International Agency for Research on Cancer Monograph Working Group In May, 2011, 30 scientists from 14 countries met at the International Agency for Research on Cancer (IARC) in Lyon, France, to assess the carcinogenicity of radiofrequency electromagnetic fields (RF-EMF). These assessments will be published as Volume 102 of the IARC Monographs.1

/pdf/carcinogenicity-of-radiofrequency-electromagnetic-fields-196dq7nv0f.pdf

Carcinogenicity of radiofrequency electromagnetic fields

Noninvasive Deep Brain Stimulation via Temporally Interfering Electric Fields

Wireless deep brain stimulation of well-defined neuronal populations could facilitate the study of intact brain circuits and the treatment of neurological disorders. Here, we demonstrate minimally invasive and remote neural excitation through the activation of the heat-sensitive capsaicin receptor TRPV1 by magnetic nanoparticles. When exposed to alternating magnetic fields, the nanoparticles dissipate heat generated by hysteresis, triggering widespread and reversible firing of TRPV1(+) neurons. Wireless magnetothermal stimulation in the ventral tegmental area of mice evoked excitation in subpopulations of neurons in the targeted brain region and in structures receiving excitatory projections. The nanoparticles persisted in the brain for over a month, allowing for chronic stimulation without the need for implants and connectors.

https://science.sciencemag.org/content/sci/347/6229/1477.full.pdf

Wireless Magnetothermal Deep Brain Stimulation

Lead-DBS v2: Towards a comprehensive pipeline for deep brain stimulation imaging.

textThe exposure of children tomobile phones has been a concern for years, but so far the conclusions with respect to compliance with safety standards are based only on simulations. Regulators have requested that these conclusions be supported by experimental evidence. The objectives of this study are 1) to test if the hypothesis that the specific anthropomorphic mannequin (SAM) used in standardized compliance testing is also conservative for homogeneous child head models and 2) to validate the numerical prediction of the peak spatial SAR (psSAR) in child head phantoms. To achieve these objectives, head phantoms of 3- and 8-yearold children were developed and manufactured. The results confirm that SAM is also conservative for child head phantoms, and that the agreement between numerical and experimental values are within the combined uncertainty of 0.9 dB, provided that the actual peak spatial SAR (psSAR) is determined. The results also demonstrate that the currently suggested numerical SAR averaging procedures may underestimate the actual psSAR by more than 1.3 dB and that the currently defined limits in terms of the average of a cubic mass are impractical for non-ambiguous evaluations, i.e., for achieving inter-laboratory repeatability. Copyright

Experimental Evaluation of the SAR Induced in Head Phantoms of Three- and Eight-Year-Old Children

In this paper, a novel applicator for hyperthermia treatment is presented providing a significantly improved quality assurance for the treatment. An improved method has been developed to measure the total incident field (amplitude and phase) and the power absorbed (SAR) by the tissues from each applicator element, based on integrated sensors and data acquisition electronics. For phased array deep RF hyperthermia this method can take into account reflection, mismatch, cross coupling and changes in any of these. Furthermore, a new treatment paradigm for superficial hyperthermia using deionised water as a dielectric waveguide to deliver power from each individual applicator to a specific region without significant impact on the divergence of the field with distance.

https://www.ursi.org/Proceedings/ProcGA14/papers/ursi_paper2617.pdf

Novel applicator for local RF hyperthermia treatment using improved excitation control

Virtual anatomical models are increasingly used for a number of applications, ranging from (non)-ionizing radiation assessment to medical treatment and implant development. Accordingly, the number of available models has been increasing rapidly during recent years, and dosimetric studies for engineering and medical purposes are blooming. Here, we discuss an example of passive implant safety assessment to demonstrate how numerical simulations results can vary with the quality and detail of particular anatomical models.

Numerical simulations in virtual anatomical models: The devil is in the details

Individual whole body and organ specific exposure for near-field and far-field exposure of radio frequency electromagnetic fields

Achieving good quality hyperthermia treatments places extremely high demands on both the applicator hardware and the treatment planning software and further requires an interface between the two modalities that guarantees precise steering and treatment delivery. We propose a paradigm that addresses all of these challenges with a flexible and light applicator, based on an innovative mask concept, placed on the patient and validated software optimized for patient-specific treatment, which together allow for high-fidelity and reproducible targeted tumor heating.

http://ieeexplore.ieee.org/iel7/7209133/7228134/07228493.pdf

Marie-Christine Gosselin

Papers

Experimental Evaluation of the SAR Induced in Head Phantoms of Three- and Eight-Year-Old Children

Novel applicator for local RF hyperthermia treatment using improved excitation control

Numerical simulations in virtual anatomical models: The devil is in the details

Individual whole body and organ specific exposure for near-field and far-field exposure of radio frequency electromagnetic fields

A new approach to high-quality patient-specific hyperthermia treatment