M
Marilyn P. Merker
Researcher at Medical College of Wisconsin
Publications - 37
Citations - 641
Marilyn P. Merker is an academic researcher from Medical College of Wisconsin. The author has contributed to research in topics: Duroquinone & Endothelial stem cell. The author has an hindex of 17, co-authored 37 publications receiving 611 citations. Previous affiliations of Marilyn P. Merker include United States Department of Veterans Affairs & Veterans Health Administration.
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Journal ArticleDOI
Intracellular redox status affects transplasma membrane electron transport in pulmonary arterial endothelial cells
Marilyn P. Merker,Robert D. Bongard,Nicholas J. Kettenhofen,Yoshiyuki Okamoto,Christopher A. Dawson +4 more
TL;DR: The results suggest that cellular redox status is a determinant of pulmonary arterial endothelial cell TPMET activity, with T PMET activity more highly correlated with the poise of the NADH/NAD(+) redox pair.
Journal ArticleDOI
Pulmonary endothelial thiazine uptake : separation of cell surface reduction from intracellular reoxidation
Marilyn P. Merker,Robert D. Bongard,John H. Linehan,Yoshiyuki Okamoto,Drahomir Vyprachticky,Becky M. Brantmeier,David L. Roerig,Christopher A. Dawson +7 more
TL;DR: The results indicate that the reduction and intracellular sequestration are separate processes and that, in doses that inhibited intrACEllular reoxidation, and therefore uptake and sequestration, neither cyanide nor azide had an inhibitory effect on extracellular reduction.
Journal ArticleDOI
Reduction of thiazine dyes by bovine pulmonary arterial endothelial cells in culture
Robert D. Bongard,Marilyn P. Merker,R. Shundo,Y. Okamoto,David L. Roerig,John H. Linehan,Christopher A. Dawson +6 more
TL;DR: The results with ferricyanide were consistent with the concept that the monomeric thiazine dyes are reduced at the cell surface before the more lipophilic reduced forms are taken up by the endothelial cells.
Journal ArticleDOI
Biotinylation of membrane proteins accessible via the pulmonary circulation in normal and hyperoxic rats.
E. K. De La Fuente,Christopher A. Dawson,Leif D. Nelin,Robert D. Bongard,Timothy L. McAuliffe,Marilyn P. Merker +5 more
TL;DR: The results demonstrate that biotinylation of membrane proteins accessible to an extracellular reagent during a single transit through the pulmonary vascular bed is feasible and that the spectrum of these labeled proteins reveals the effects of hyperoxic lung injury.
Journal ArticleDOI
Quantifying mitochondrial and plasma membrane potentials in intact pulmonary arterial endothelial cells based on extracellular disposition of rhodamine dyes.
Zhuohui Gan,Said H. Audi,Robert D. Bongard,Kathryn M. Gauthier,Marilyn P. Merker,Marilyn P. Merker +5 more
TL;DR: The consistency of kinetic parameter values obtained from R123 and TMRE data demonstrates the utility of this experimental and theoretical approach for quantifying intact cell Δψ(m) and Δ ψ(p.)