An overview of the wide range of nanoreactors that have been constructed from synthetic and biological building blocks using both covalent and noncovalent approaches is given. Focus is on self-assembled systems, varying in size from a few nanometers to tens of micrometers. The review is divided into several sections that cover the development of tailor-made nanoreactors, starting from small organic molecular containers expanding to large compartment-containing assemblies. First, the construction of capsules from low molecular weight compounds by means of covalent synthesis and self-assembly by highly directive and pre-designed interactions is discussed. Second, nanocapsules based on micellar and vesicular assemblies that are built up frow low molecular weight molecules are described. Finally, the construction of nanoreactors from macromolecular building blocks, as well as recent developments in the use of viruses as nanocontainers and reactors are outlined.

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Self-Assembled Nanoreactors

Laboratory for Advanced Materials and New Catalysis, School of Chemistry and Materials Science, Hubei University, Wuhan 430062, China,Laboratory of Natural Gas Utilization and Applied Catalysis, Dalian Institute of Chemical Physics of Chinese Academy of Sciences, Dalian 116023,China, and Jingmen Technological College, Jingmen 448000, ChinaReceived June 30, 2004

Advances in Homogeneous and Heterogeneous Catalytic Asymmetric Epoxidation

Advances in the chemistry of tetrahydroquinolines.

http://www.tara.tcd.ie/bitstream/handle/2262/50689/Asymmetric.pdf?sequence=1

Asymmetric catalysis with bifunctional cinchona alkaloid-based urea and thiourea organocatalysts.

C2-Symmetric Chiral Bis(Oxazoline) Ligands in Asymmetric Catalysis

Ab initio calculations of the optical rotatory power of the natural cytokine modulator cytoxazone 1 and its trans-diastereomer 2, as well as the structural isomers cis-3 and trans-4 isocytoxazones, have been performed at four different wavelengths (589, 546, 435, and 405 nm) by Density Functional Theory. The calculation of ORD curves provides a reliable method for the assignment of absolute configuration of these conformationally flexible molecules. The absolute configurations of isocytoxazones has been established as (+)-(4R,5S)-cis-3 and (+)-(4S,5S)-trans-4.

/pdf/determination-of-the-absolute-configuration-of-flexible-434rhxka5c.pdf

Determination of the absolute configuration of flexible molecules by ab initio ORD calculations: a case study with Cytoxazones and Isocytoxazones

Pyridyl and Furyl Epoxides of More Than 99% Enantiomeric Purities: The Use of a Phosphazene Base

Four endo -isomers of (1 R ,2 S )-2-amino-4-methylenecyclopentanecarboxylic acid (+)- 1 (Icofungipen) have been prepared in enantiomerically pure form. Three endo -isomers were obtained by quinine-mediated kinetic resolution of a racemic anhydride, followed by Curtius rearrangement. The fourth isomer was obtained by an exo – endo isomerization of (+)- 1 . The assignment of the absolute configuration is based either on the Cotton effect in the CD spectra or in correlation to already known structures.

Quinine-mediated parallel kinetic resolution of racemic cyclic anhydride: stereoselective synthesis, relative and absolute configuration of novel alicyclic β-amino acids

The aim of this work was to perform the phytochemical analysis as well as antioxidant and anticholinesterase potential of hot water and methanolic extracts from Mentha pulegium L., Lamiaceae, wild growing in Bosnia and Herzegovina. It is a plant that is traditionally used in Bosnia and Herzegovina medicine to treat gastrointestinal and neurological disorders. By HPLC-DAD analysis of tested extracts, 15 phenol compounds were identified and quantified. Rosmarinic acid was the most abundant compound in both extracts, followed by ellagic acid, eriodictyol, naringenin and chlorogenic acid. Both extracts were demonstrated good radical scavenging potential, reducing power and ability to inhibit lipid oxidation. The tested extracts also showed low ability to inhibit protein oxidation and low or no acetylcholinesterase and butyrylcholinesterase inhibition potential. The promising radical scavenging potential, reducing power and lipid protection potential of tested extracts indicates that the extracts of M. pulegium could be useful in preventing free radical linked diseases, as well as food protecting antioxidants.

Marin Roje

Papers

Determination of the absolute configuration of flexible molecules by ab initio ORD calculations: a case study with Cytoxazones and Isocytoxazones

Pyridyl and Furyl Epoxides of More Than 99% Enantiomeric Purities: The Use of a Phosphazene Base

Quinine-mediated parallel kinetic resolution of racemic cyclic anhydride: stereoselective synthesis, relative and absolute configuration of novel alicyclic β-amino acids

Phytochemical Composition, Antioxidant Potential and Cholinesterase Inhibition Potential of Extracts from Mentha pulegium L.

Chiral Macrocyclic Bis(oxazoline) CuI Complexes – Structure/Stereoselectivity Relationships in Catalytic Cyclopropanations