M
Marion Lyght
Researcher at National Institutes of Health
Publications - 1
Citations - 1923
Marion Lyght is an academic researcher from National Institutes of Health. The author has contributed to research in topics: Growth factor & Inflammation. The author has an hindex of 1, co-authored 1 publications receiving 1855 citations.
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Transforming growth factor beta 1 null mutation in mice causes excessive inflammatory response and early death.
Ashok B. Kulkarni,Chang-Goo Huh,Dean Becker,Andrew G. Geiser,Marion Lyght,Kathleen C. Flanders,Anita B. Roberts,Michael B. Sporn,Jerrold M. Ward,Stefan Karlsson +9 more
TL;DR: Pathological examination revealed an excessive inflammatory response with massive infiltration of lymphocytes and macrophages in many organs, but primarily in heart and lungs, which suggests a prominent role for TGF-beta 1 in homeostatic regulation of immune cell proliferation and extravasation into tissues.