Mark Ratner

TL;DR: Colon cancer drug increases risk of embolisms, but not as much as previously thought, according to a study in the Journal of Clinical Oncology.

TL;DR: Pfizer is rolling out a grand plan to draw out drug-development-ready research from academia through a series of collaborations with leading medical centers worldwide, and its CTIs will seek out investigators who have already developed a hypothesis around a novel disease mechanism and are keen to translate their discoveries into drugs.

TL;DR: Pfizer will compete with Genzyme's Ceredase (alglucerase) and Cerezyme for the treatment of Gaucher’s disease with its prGCD, a form of the enzyme beta-glucocerebrosidase purified from human placental tissue that is modified to be terminated with mannose.

TL;DR: Expression systems are protein specific and you must be able to play around with each one, insert your gene of choice, tweak it, and then see what you've got.