M
Mark Vincent
Researcher at University of Western Ontario
Publications - 125
Citations - 4206
Mark Vincent is an academic researcher from University of Western Ontario. The author has contributed to research in topics: Lung cancer & Cancer. The author has an hindex of 31, co-authored 110 publications receiving 3769 citations. Previous affiliations of Mark Vincent include University of British Columbia & Lawson Health Research Institute.
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Journal ArticleDOI
Randomized Phase III Study of Cisplatin With or Without Raltitrexed in Patients With Malignant Pleural Mesothelioma: An Intergroup Study of the European Organisation for Research and Treatment of Cancer Lung Cancer Group and the National Cancer Institute of Canada
Jan P. van Meerbeeck,Rabab Gaafar,Christian Manegold,Rob J. van Klaveren,Eric Van Marck,Mark Vincent,Catherine Legrand,Andrew Bottomley,C. Debruyne,Giuseppe Giaccone +9 more
TL;DR: It is confirmed that a combination of cis platin and an antifolate is superior to cisplatin alone in patients with MPM, without harmful effect on HRQOL.
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Randomized Phase III Trial of Vinorelbine Plus Cisplatin Compared With Observation in Completely Resected Stage IB and II Non–Small-Cell Lung Cancer: Updated Survival Analysis of JBR-10
Charles A. Butts,Keyue Ding,Lesley Seymour,Philip Twumasi-Ankrah,Barbara Graham,David R. Gandara,David H. Johnson,Kenneth A. Kesler,Mark A. Green,Mark Vincent,Yvon Cormier,Glenwood D. Goss,B. Findlay,Michael R. Johnston,Ming-Sound Tsao,Frances A. Shepherd +15 more
TL;DR: Prolonged follow-up of patients from the JBR10 trial continues to show a benefit in survival for adjuvant chemotherapy, and this benefit appears to be confined to N1 patients.
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Multicenter Phase III Study of Uracil/Tegafur and Oral Leucovorin Versus Fluorouracil and Leucovorin in Patients With Previously Untreated Metastatic Colorectal Cancer
Jean-Yves Douillard,Paulo M. Hoff,J. Skillings,Peter D. Eisenberg,Neville Davidson,Peter Harper,Mark Vincent,Barry C. Lembersky,Seth Thompson,Antonella Maniero,Steven E. Benner +10 more
TL;DR: UFT/LV provided a safer, more convenient oral alternative to a standard bolus IV 5-FU/LV regimen for metastatic colorectal cancer while producing equivalent survival.
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Continued Cigarette Smoking by Patients Receiving Concurrent Chemoradiotherapy for Limited-Stage Small-Cell Lung Cancer Is Associated With Decreased Survival
Gregory M.M Videtic,Larry W. Stitt,A. Rashid Dar,Walter Kocha,Anna Tomiak,P. Truong,Mark Vincent,Edward Yu +7 more
TL;DR: LSCLC patients who continue to smoke during chemoradiotherapy during CHT/RT have poorer survival rates than those who do not, and smoking did not have an impact on the rate of treatment interruptions attributed to toxicity.
Journal ArticleDOI
Prevention and management of chemotherapy-induced diarrhea in patients with colorectal cancer: a consensus statement by the Canadian Working Group on Chemotherapy-Induced Diarrhea.
J. Maroun,Lowell Anthony,Normand Blais,Ronald Burkes,Scot D. Dowden,George Dranitsaris,B. Samson,A Shah,M. Thirlwell,Mark Vincent,R. Wong +10 more
TL;DR: Acute medical management of cid includes loperamide or diphenoxylate as first-line agents and hospitalization is recommended for patients with grades 3 and 4 cid; in-hospital care includes rehydration, antibiotic therapy, and octreotide.