M
Marshall W. Lightowlers
Researcher at University of Melbourne
Publications - 223
Citations - 9235
Marshall W. Lightowlers is an academic researcher from University of Melbourne. The author has contributed to research in topics: Echinococcus granulosus & Taenia solium. The author has an hindex of 50, co-authored 219 publications receiving 8621 citations. Previous affiliations of Marshall W. Lightowlers include Walter and Eliza Hall Institute of Medical Research & Commonwealth Scientific and Industrial Research Organisation.
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Journal ArticleDOI
Prevention and control of cystic echinococcosis
Philip S. Craig,Donald P. McManus,Marshall W. Lightowlers,José A. Chabalgoity,Hector H. Garcia,Hector H. Garcia,Cesar M. Gavidia,Cesar M. Gavidia,Robert H. Gilman,Robert H. Gilman,Armando E. Gonzalez,Armando E. Gonzalez,Myriam Lorca,César Náquira,Alberto Nieto,Peter M. Schantz +15 more
TL;DR: Since the introduction of current (and past) hydatid control campaigns, there have been clear technological improvements made in the diagnosis and treatment of human and animal cystic echinococcosis, the diagnosis of canine echinocentrosis, and the genetic characterisation of strains and vaccination against Echinococcus granulosus in animals.
Journal ArticleDOI
Echinococcus granulosus sensu lato genotypes infecting humans--review of current knowledge.
TL;DR: Biological differences between the species and genotypes have potential to affect the transmission dynamics of the parasite, requiring modification of methods used in disease control initiatives.
Journal ArticleDOI
Vaccination against ovine cysticercosis using a defined recombinant antigen.
Kevin S. Johnson,G.B.L. Harrison,Marshall W. Lightowlers,K. L. O'Hoy,W. G. Cougle,R.P. Dempster,S.B. Lawrence,J. G. Vinton,David D. Heath,Michael D. Rickard +9 more
TL;DR: The expression in Escherichia coli of complementary DNA encoding T. ovis antigens as fusion proteins with the Schistosoma japonicum glutathione S-transferase gives significant, although not complete, immunity against challenge infection with T. Ovis eggs.
Journal ArticleDOI
Vaccination against hydatidosis using a defined recombinant antigen
Marshall W. Lightowlers,S.B. Lawrence,Charles G. Gauci,J. Young,M. J. Ralston,D. Maas,David D. Heath +6 more
TL;DR: The development of a vaccine based on a cloned recombinant antigen from the parasite egg (oncosphere), designated EG95, is described, which has the potential to prevent hydatid disease directly through vaccination of humans.
Journal ArticleDOI
Excretory-secretory products of helminth parasites: effects on host immune responses.
TL;DR: It is proposed that the active shedding of surface antIGens may serve as an important source of parasite antigens available to the immune system in a form in which they can be taken up and processed by antigen-presenting dendritic cells, macrophages and certain B cells for presentation to T helper cells.