M
Martin A. Read
Researcher at Institute of Cancer Research
Publications - 19
Citations - 1952
Martin A. Read is an academic researcher from Institute of Cancer Research. The author has contributed to research in topics: Telomerase & G-quadruplex. The author has an hindex of 14, co-authored 19 publications receiving 1861 citations. Previous affiliations of Martin A. Read include King's College London.
Papers
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Journal ArticleDOI
A Novel Inhibitor of Human Telomerase Derived from 10H-Indolo[3,2-b]quinoline.
Vittorio Caprio,Berengere Guyen,Yaw Opoku-Boahen,John Mann,John Mann,Sharon Gowan,Lloyd M. Kelland,Martin A. Read,Stephen Neidle +8 more
TL;DR: The bis-dimethylaminoethyl derivative of quindoline (10H-indolo[3,2-b]quinoline), an alkaloid from the West African shrub Cryptolepis sanguinolenta, has been synthesised and has been shown to have modest cytotoxicity, as well as inhibitory activity against the telomerase enzyme.
Journal ArticleDOI
2′,3′-Anhydrouridine. A Useful Synthetic Intermediate.
Anwar Miah,Colin B. Reese,Quanlai Song,Zoë Sturdy,Stephen Neidle,I.J. Simpson,Martin A. Read,Emma L. Rayner +7 more
TL;DR: In this paper, the 2,2′-anhydronucleoside was shown to react with an excess of potassium tert-butoxide in DMSO to yield 3,5′-Anhydrouridine.
Patent
Composes therapeutiques d'acridone et d'acridine
Sharon Gowan,Richard J. Harrison,Lloyd Royston Kelland,Stephen Neidle,Martin A. Read,Tony Reszka +5 more
TL;DR: The authors concerne des compositions pharmaceutiques comprenant de tels composes, ainsi que lutilisation de ces composes and de ce compositions, a la fois in vitro and in vivo, afin d'inhiber la telomerase, de reguler la proliferation cellulaire, and des formes protegees.