M
Martina Santarsieri
Researcher at University of Pittsburgh
Publications - 3
Citations - 229
Martina Santarsieri is an academic researcher from University of Pittsburgh. The author has contributed to research in topics: Traumatic brain injury & Luteinizing hormone. The author has an hindex of 3, co-authored 3 publications receiving 206 citations.
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Journal ArticleDOI
Acute Serum Hormone Levels: Characterization and Prognosis after Severe Traumatic Brain Injury
Amy K. Wagner,Emily H. McCullough,Christian Niyonkuru,Haishin Ozawa,Tammy L. Loucks,Julie A. Dobos,Christopher A. Brett,Martina Santarsieri,C. Edward Dixon,Sarah L. Berga,Anthony Fabio +10 more
TL;DR: Findings represent a paradigm shift when thinking about the role of sex steroids in neuroprotection clinically after TBI, as increased estradiol and testosterone levels over time were associated with increased mortality and worse global outcome for both men and women.
Journal ArticleDOI
Cerebrospinal fluid cortisol and progesterone profiles and outcomes prognostication after severe traumatic brain injury.
Martina Santarsieri,Christian Niyonkuru,Emily H. McCullough,Julie A. Dobos,C. Edward Dixon,Sarah L. Berga,Amy K. Wagner +6 more
TL;DR: Serum and CSF levels for both cortisol and progesterone were strongly correlated after TBI relative to controls, possibly because of blood-brain barrier disruption.
Journal ArticleDOI
Variable neuroendocrine-immune dysfunction in individuals with unfavorable outcome after severe traumatic brain injury
TL;DR: The results suggest that unfavorable outcome after TBI may result from dysfunctional neuroendocrine-immune communication wherein an adequate immune response is not mounted or, alternatively, neuroinflammation is prolonged.