M
Masaharu Onoue
Publications - 1
Citations - 993
Masaharu Onoue is an academic researcher. The author has contributed to research in topics: Interleukin 21 & Cellular differentiation. The author has an hindex of 1, co-authored 1 publications receiving 924 citations.
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ATP drives lamina propria T H 17 cell differentiation
Koji Atarashi,Junichi Nishimura,Tatsuichiro Shima,Yoshinori Umesaki,Masahiro Yamamoto,Masaharu Onoue,Hideo Yagita,Naoto Ishii,Richard J. Evans,Kenya Honda,Kiyoshi Takeda +10 more
TL;DR: It is shown that adenosine 5′-triphosphate (ATP) that can be derived from commensal bacteria activates a unique subset of lamina propria cells, CD70highCD11clow cells, leading to the differentiation of TH17 cells, and the critical role of ATP is underscored.