M
Masako Nakagawa
Researcher at Chiba University
Publications - 187
Citations - 2648
Masako Nakagawa is an academic researcher from Chiba University. The author has contributed to research in topics: Total synthesis & Indole test. The author has an hindex of 29, co-authored 187 publications receiving 2597 citations. Previous affiliations of Masako Nakagawa include Kanagawa University & Fudan University Shanghai Medical College.
Papers
More filters
Journal ArticleDOI
Peroxidic intermediates in photosensitized oxygenation of tryptophan derivatives
Journal ArticleDOI
A novel synthesis of substituted quinolines using ring-closing metathesis (RCM): its application to the synthesis of key intermediates for anti-malarial agents
TL;DR: In this paper, a method for synthesizing substituted quinolines using ruthenium-catalyzed ring-closing metathesis as a key step has been developed.
Journal ArticleDOI
A valid model for the mechanism of oxidation of tryptophan to formylkynurenine-25 years later.
Masako Nakagawa,Hideyuki Watanabe,Shin-ichi Kodato,Haruo Okajima,Tohru Hino,Judith L. Flippen,Bernhard Witkop +6 more
TL;DR: The mechanism of the smooth thermal rearrangement of the (presumably ring-chain tautomeric) tryptophan hydroperoxy intermediates to formylkynurenine is discussed with its implications for the biological oxidation by tryPTophan 2,3-dioxygenase.
Journal ArticleDOI
Development of novel EDG3 antagonists using a 3D database search and their structure-activity relationships.
Yuuki Koide,Takeshi Hasegawa,Atsuo Takahashi,Akira Endo,Naoki Mochizuki,Masako Nakagawa,Atsushi Nishida +6 more
TL;DR: Because precise structural information on EDG receptors is not yet available, pharmacophore models were generated based on structural information for S1P using the rational drug design software Catalyst, and more potent antagonists, 2-alkylthiazolidine-4-carboxylic acid, were developed.
Journal ArticleDOI
Crystallographic and Functional Studies of Very Short Patch Repair Endonuclease
Susan E. Tsutakawa,Takanori Muto,Tomohiko Kawate,Hisato Jingami,Naoki Kunishima,Mariko Ariyoshi,Daisuke Kohda,Masako Nakagawa,Kosuke Morikawa +8 more
TL;DR: VVsr endonuclease plays a crucial role in the repair of TG mismatched base pairs, which are generated by the spontaneous degradation of methylated cytidines; Vsr recognizes the mismatch and cleaves the phosphate backbone 5' to the thymidine.