M
Masataka Hikota
Researcher at Hokkaido University
Publications - 14
Citations - 424
Masataka Hikota is an academic researcher from Hokkaido University. The author has contributed to research in topics: Polyketide & Enantioselective synthesis. The author has an hindex of 6, co-authored 14 publications receiving 416 citations.
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Synthesis of erythronolide a via a very efficient macrolactonization under usual acylation conditions with the Yamaguchi reagent
TL;DR: Macrolactonization of 3,5- O -(3,4-dimethoxybenzylidene)-9,11-O -(2,4,6-trimethylbenzo-idene)(9 S )-9-dihydroerythronolide A seco-acid (4 ) was reexamined under various conditions and found to proceed rapidly only by treatment of 4 with Yamaguchi's reagent, 2.4, 6-trichlorobenzoyl chloride, in the presence
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Chiral synthesis of polyketide-derived natural products. 27. Stereoselective synthesis of erythronolide A via an extremely efficient macrolactonization by the modified Yamaguchi method
TL;DR: La synthese du dihydro erythronolide A s'effectue a partir du glucose via un traitement avec la dimethylamino-4 pyridine.
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Stereoselective synthesis of erythronolide a by extremely efficient lactonization based on conformational adjustment and high activation of seco-acid1
TL;DR: In this paper, Yamaguchi's mixed anhydride of 7 was treated with a high concentration of DMAP at room temperature, and a very rapid cyclization occurred and the 14-membered lactone (8) was isolated in almost quantitative yield.
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A stereoselective total synthesis of (9S)-9-dihydroerythronolide A from D-glucose☆
TL;DR: A rather facile stereoselective total synthesis of (9S)-9-dihydroerythronolide was achieved via coupling of C1-C6 and C7-C15 segments and subsequent macrolactonization as mentioned in this paper.
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Diels-alder reaction of chiral dienes. Remarkable effect of dienophile polarity upon diastereo face selectivity
TL;DR: In this paper, the face selectivity of diels-alder reaction of diene having the stereogenic center at allylic position depends on dienophile polarity, and hetero Diels-Alder reaction with Dienophile such as N-tosylimine and N-sulfinylimine was found to give exclusively ul product.