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Massimiliano Tognolini

Researcher at University of Parma

Publications -  81
Citations -  4329

Massimiliano Tognolini is an academic researcher from University of Parma. The author has contributed to research in topics: Ephrin & Erythropoietin-producing hepatocellular (Eph) receptor. The author has an hindex of 27, co-authored 77 publications receiving 3712 citations. Previous affiliations of Massimiliano Tognolini include University of Pennsylvania.

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Dietary (Poly)phenolics in Human Health: Structures, Bioavailability, and Evidence of Protective Effects Against Chronic Diseases

TL;DR: It is concluded that better performed in vivo intervention and in vitro mechanistic studies are needed to fully understand how (poly)phenol molecules interact with human physiological and pathological processes.
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Comparative screening of plant essential oils: phenylpropanoid moiety as basic core for antiplatelet activity.

TL;DR: For these oils a significant correlation between antiplatelet potency and phenylpropanoids content was evidenced thus suggesting a key role for this moiety in the prevention of clot formation.
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Protective Effect of Foeniculum Vulgare Essential Oil and Anethole in an Experimental Model of Thrombosis

TL;DR: Results demonstrate for F. vulgare essential oil, and its main component anethole, a safe antithrombotic activity that seems due to their broad spectrum antiplatelet activity, clot destabilizing effect and vasorelaxant action.
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Bioactivities of Piper aduncum L. and Piper obliquum Ruiz & Pavon (Piperaceae) essential oils from Eastern Ecuador.

TL;DR: Preliminary analgesic and antithrombotic activities evidenced the absence of the former in hot plate and edema assays and a limited antiplatelet action against three different agonists (ADP, AA and U46619).
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Synthesis, antiplatelet and antithrombotic activities of new 2-substituted benzopyrano[4,3-d]pyrimidin-4-cycloamines and 4-amino/cycloamino-benzopyrano[4,3-d]pyrimidin-5-ones.

TL;DR: Novel antithrombotic compounds with an interesting pharmacological profile and a potentially attractive benefit/risk ratio are described, with their mechanism of action generally, but not exclusively, dependent on antiplatelet activity, deserving further investigations.