M
Massimo Coletta
Researcher at University of Rome Tor Vergata
Publications - 254
Citations - 5803
Massimo Coletta is an academic researcher from University of Rome Tor Vergata. The author has contributed to research in topics: Heme & Ferrous. The author has an hindex of 38, co-authored 246 publications receiving 5160 citations. Previous affiliations of Massimo Coletta include University of Salerno & University of Camerino.
Papers
More filters
Journal ArticleDOI
Human matrix metalloproteinases: an ubiquitarian class of enzymes involved in several pathological processes.
Diego Sbardella,Giovanni Francesco Fasciglione,Magda Gioia,Chiara Ciaccio,Grazia R. Tundo,Stefano Marini,Massimo Coletta +6 more
TL;DR: An extensive review of the different MMPs structural and functional features is integrated with their pathological role in several types of diseases, spanning from cancer to cardiovascular diseases and to neurodegeneration.
Journal ArticleDOI
The Bovine Basic Pancreatic Trypsin Inhibitor (Kunitz Inhibitor): A Milestone Protein
Paolo Ascenzi,Alessio Bocedi,Martino Bolognesi,Andrea Spallarossa,Massimo Coletta,Raimondo De Cristofaro,Enea Menegatti +6 more
TL;DR: The structural, inhibition, and bio-medical aspects of BPTI are reported, which include inhibition of nitric oxide synthase type-I and -II action and impairs K+ transport by Ca2+-activated K+ channels.
Journal ArticleDOI
Insights into cytochrome c-cardiolipin interaction. Role played by ionic strength.
Federica Sinibaldi,Laura Fiorucci,Antonella Patriarca,Rosaria Lauceri,Tommaso Ferri,Massimo Coletta,Roberto Santucci +6 more
TL;DR: This paper found that formation of the cytochrome c-cardiolipin complex occurs via two distinct transitions, implying a high-affinity site and a low-Affinity site in the complex, and ascribes it to the high activation barrier met by the protein when restoring the native Fe(III)-M80 axial bond.
Journal ArticleDOI
Aβ(31–35) and Aβ(25–35) fragments of amyloid beta-protein induce cellular death through apoptotic signals: Role of the redox state of methionine-35
M. Elisabetta Clementi,Stefano Marini,Massimo Coletta,Federica Orsini,Bruno Giardina,Francesco Misiti +5 more
TL;DR: Taken together, this result indicate that Aβ(31–35) and A β(25– 35) peptides in non‐aggregated form, i.e., predominantly monomeric, are strongly neurotoxic, having the ability to enter within the cells, determining mitochondrial damage with an evident trigger of apoptotic signals.
Journal ArticleDOI
Extended cardiolipin anchorage to cytochrome c : a model for protein–mitochondrial membrane binding
Federica Sinibaldi,Barry D. Howes,Maria Cristina Piro,Fabio Polticelli,Cecilia Bombelli,Tommaso Ferri,Massimo Coletta,Giulietta Smulevich,Roberto Santucci +8 more
TL;DR: A spectroscopic and kinetic study of the wild type and the Asn52Ile mutant of iso-1-cytochrome c from yeast is undertaken to investigate the interaction of cy tochrome c with CL vesicles, considered here a model for the CL-containing mitochondrial membrane.