Recent developments in the chemistry of enaminones

Synthesis of heterocycles from alkyl 3-(dimethylamino)propenoates and related enaminones.

4-(4,6-dimethoxy-1,3,5-triazin-2-yl)-4-methyl-morpholinium chloride: an efficient condensing agent leading to the formation of amides and esters

Synthesis and characterization of 4-(4,6-dimethoxy-1,3,5-triazin-2-yl)-4-methylmorpholinium chloride

Protection for the Amino Group

2‐Benzoyl‐2‐ethoxycarbonylvinyl‐1 and 2‐benzoylamino‐2‐methoxy‐carbonylvinyl‐1 as N‐protecting groups in peptide synthesis. Their application in the synthesis of dehydropeptide derivatives containing N‐terminal 3‐heteroarylamino‐2,3‐dehydroalanine

The transformations of 4-heteroarylaminomethylene-5(4h)-oxazolones into dehydropeptide derivatives

2-Phenyl-4-heteroarylaminomethylene-5(4H)-oxazolones 3, which were prepared from the corresponding N,N-dimethyl-N'-heteroarylformamidines 1 and hippuric acid 2 in acetic anhydride, react with amino acids giving dehydropeptide derivatives 4, 5, and 6 as products. Dehydration of N-protected peptides 7–10, containing glycine at the C-terminal, followed by the reaction with formamidines 1 gave 2-substituted-4-heteroarylaminomethylene-5(4H)-oxazolones 11–14.

The Transformations of 4‐Heteroarylaminomethylene‐5(4H)‐oxazolones into Dehydropeptide Derivatives.

3-Benzoyl-2-ethoxycarbonylvinyl-1 and 2-Benzoylamino-2- methoxycarbonylvinyl-1 as N-Protecting Groups in Peptide Synthesis. Their Application in the Synthesis of Dehydropeptide Derivatives Containing N-Terminal 3-Heteroarylamino-2,3-dehydroalanine.

Mateja Aljaẑ-Roẑiĉ

Papers

2‐Benzoyl‐2‐ethoxycarbonylvinyl‐1 and 2‐benzoylamino‐2‐methoxy‐carbonylvinyl‐1 as N‐protecting groups in peptide synthesis. Their application in the synthesis of dehydropeptide derivatives containing N‐terminal 3‐heteroarylamino‐2,3‐dehydroalanine

The transformations of 4-heteroarylaminomethylene-5(4h)-oxazolones into dehydropeptide derivatives

The Transformations of 4‐Heteroarylaminomethylene‐5(4H)‐oxazolones into Dehydropeptide Derivatives.

3-Benzoyl-2-ethoxycarbonylvinyl-1 and 2-Benzoylamino-2- methoxycarbonylvinyl-1 as N-Protecting Groups in Peptide Synthesis. Their Application in the Synthesis of Dehydropeptide Derivatives Containing N-Terminal 3-Heteroarylamino-2,3-dehydroalanine.