Showing papers by "Mathieu F. Janssen published in 2008"
TL;DR: The EQ-5D five-level version appears a valid and reliable extension of the three-level system and is particularly useful for describing mild health problems and monitoring population health.
223 citations
TL;DR: This methodological study provides evidence of increased descriptive power and a broadened measurement continuum that encourages the further development of an official five-level EQ-5D.
Abstract: Objectives
Our aim was to compare the quantitative position of the level descriptors of the standard EQ-5D three-level system (3L) and a newly developed, experimental five-level version (5L) using a direct and a vignette-based indirect method.
69 citations
TL;DR: The annual profile method (APM), which values health profiles on a 1-year base, is presented and a promising step to bridge the gap between the quality-adjusted life year methodology and clinical reality is tested.
Abstract: Introduction . When health varies over time, the standard quality-adjusted life year model operates under the assumptions of time utility independence within each health state and additive independence between health states. These assumptions can be relaxed by an integral assessment of disease severity over time. The authors present the annual profile method (APM), which values health profiles on a 1-year base, and test the APM for feasibility, consistency, and test-retest reliability.Methods. A population panel, general practitioners, medical advisers, and a panel of the Dutch Consumers Association valued vignettes for 46 disease stages using the visual analog scale (VAS) and time tradeoff (TTO) methods. Vignettes contained disease-specific information, a generic description (EQ-6D5L), a description of the disease course over time, and a visual representation of the disease. Feasibility was tested by missing and inconsistent responses. Consistency between and within panels was tested with a generalizabil...
19 citations