M
Matthew A Teten
Publications - 2
Citations - 4
Matthew A Teten is an academic researcher. The author has contributed to research in topics: Chemistry & Medicine. The author has an hindex of 1, co-authored 2 publications receiving 4 citations.
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Journal ArticleDOI
Towards continuous mAb purification: Clearance of host cell proteins from CHO cell culture harvests via “flow‐through affinity chromatography” using peptide‐based adsorbents
Sobhana A. Sripada,Wen-Ping Chu,Taufika Islam Williams,Matthew A Teten,Brian J Mosley,Ruben G. Carbonell,Abraham M. Lenhoff,Steven M. Cramer,Jerome Bill,Yinges Yigzaw,David J. Roush,Stefano Menegatti +11 more
TL;DR: An ensemble of peptide ligands that target the HCPs in Chinese hamster ovary (CHO) cell culture fluids and enable mAb purification via flow‐through affinity chromatography are introduced and their integration into LigaGuard™, an affinity adsorbent featuring an equilibrium binding capacity.
Journal ArticleDOI
Enrichment of adeno-associated virus serotype 5 full capsids by anion exchange chromatography with dual salt elution gradients.
R Ashton Lavoie,Jeffrey T. Zugates,Matthew A Teten,Srivatsan Ramesh,Amod Joshi,Bradley Christopher Hollers,Zufan Debebe,Eric J. Yearley,Alexander Tracy +8 more
TL;DR: In this paper , anion exchange chromatography was used to achieve empty and full capsid resolution for adeno-associated virus serotype 5, and a salt gradient screen of multiple salts with varied valency and Hofmeister series properties was performed to determine optimal peak resolution and aggregate reduction.