S
Stefano Menegatti
Researcher at North Carolina State University
Publications - 110
Citations - 2292
Stefano Menegatti is an academic researcher from North Carolina State University. The author has contributed to research in topics: Peptide & Chemistry. The author has an hindex of 18, co-authored 89 publications receiving 1621 citations. Previous affiliations of Stefano Menegatti include University of California, Santa Barbara & Durham University.
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Journal ArticleDOI
Elasticity of nanoparticles influences their blood circulation, phagocytosis, endocytosis, and targeting.
Aaron C. Anselmo,Mengwen Zhang,Sunny Kumar,Douglas R. Vogus,Stefano Menegatti,Matthew E. Helgeson,Samir Mitragotri +6 more
TL;DR: Tuning nanoparticle elasticity potentially offers a method to improve the biological fate of nanoparticles by offering enhanced circulation, reduced immune system uptake, and improved targeting.
Journal ArticleDOI
Platelet-like Nanoparticles: Mimicking Shape, Flexibility, and Surface Biology of Platelets To Target Vascular Injuries
Aaron C. Anselmo,Christa L. Modery-Pawlowski,Stefano Menegatti,Sunny Kumar,Douglas R. Vogus,Lewis L. Tian,Ming Chen,Todd M. Squires,Anirban Sen Gupta,Samir Mitragotri +9 more
TL;DR: Platelet-like nanoparticles (PLNs) offer a nanoscale technology that integrates platelet-mimetic biophysical and biochemical properties for potential applications in injectable synthetic hemostats and vascularly targeted payload delivery.
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Performance of hexamer peptide ligands for affinity purification of immunoglobulin G from commercial cell culture media.
TL;DR: Issues related to the successful application of the hexapeptide ligands, on a commercial methacrylate chromatographic resin, for the purification of IgG from mammalian cell culture fluids are addressed.
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Peptides as skin penetration enhancers: mechanisms of action.
TL;DR: Among the peptides tested, SPACE peptide was found to be least toxic to keratinocytes, and among the most effective at delivering CsA into the skin.
Journal ArticleDOI
Synergistic antitumor activity of camptothecin-doxorubicin combinations and their conjugates with hyaluronic acid.
Kathryn M. Camacho,Sunny Kumar,Stefano Menegatti,Douglas R. Vogus,Aaron C. Anselmo,Samir Mitragotri +5 more
TL;DR: This study elucidates a method to identify synergistic drug combinations and translate them to in vivo by preserving the synergistic ratio via conjugation to a carrier polymer, thus opening a promising approach to translate drug combinations to clinically viable treatment regimens.