M
Matthew M. Winkler
Researcher at Woodward, Inc.
Publications - 25
Citations - 866
Matthew M. Winkler is an academic researcher from Woodward, Inc.. The author has contributed to research in topics: Nucleic acid & Nucleic acid methods. The author has an hindex of 12, co-authored 24 publications receiving 851 citations.
Papers
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Journal ArticleDOI
Armored RNA Technology for Production of Ribonuclease-Resistant Viral RNA Controls and Standards
Brittan L. Pasloske,Cindy R. WalkerPeach,R. Dawn Obermoeller,Matthew M. Winkler,Dwight B. DuBois +4 more
TL;DR: The development of a versatile, novel system for creating RNase-resistant RNA that was shown to be resistant to degradation in human plasma and produced reproducible results in the Amplicor HIV-1 Monitor assay.
Patent
Ribonuclease resistant viral RNA standards
TL;DR: In this article, a recombinant nucleic acid is encapsidated by bacteriophage proteins and the recombinant RNA in its packaged form is highly resistant to ribonucleases and is not compromised by inadvertent ribonuclease contamination.
Patent
Comparative analysis of nucleic acids using population tagging
Matthew M. Winkler,David Brown +1 more
TL;DR: In this article, the authors present methods that allow one or more nucleic acid targets to be compared across two or more samples, such that each sample has a unique tag and the amplification products are distinguished using the unique tag domains to reveal the abundance of the amplification product derived from each sample.
Patent
Nuclease inhibitor cocktail
TL;DR: In this article, methods and compositions for inhibiting and/or inactivating nucleases by employing nuclease inhibitors are provided, which include anti-nuclease antibodies and non-antibody nucle inhibitors.
Journal ArticleDOI
Ribonuclease-resistant RNA Controls (Armored RNA) for Reverse Transcription-PCR, Branched DNA, and Genotyping Assays for Hepatitis C Virus
TL;DR: The HCV-2b Armored RNA control is a versatile, durable, ribonuclease-resistant viral RNA control that is compatible in three different clinical assay formats.