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Using Multivariate Statistics

Objective: Parkinson’s disease (PD) is a progressive neurological disorder characterised by a large number of motor and non-motor features that can impact on function to a variable degree. This review describes the clinical characteristics of PD with emphasis on those features that differentiate the disease from other parkinsonian disorders. Methods: A MedLine search was performed to identify studies that assess the clinical characteristics of PD. Search terms included “Parkinson’s disease”, “diagnosis” and “signs and symptoms”. Results: Because there is no definitive test for the diagnosis of PD, the disease must be diagnosed based on clinical criteria. Rest tremor, bradykinesia, rigidity and loss of postural reflexes are generally considered the cardinal signs of PD. The presence and specific presentation of these features are used to differentiate PD from related parkinsonian disorders. Other clinical features include secondary motor symptoms (eg, hypomimia, dysarthria, dysphagia, sialorrhoea, micrographia, shuffling gait, festination, freezing, dystonia, glabellar reflexes), non-motor symptoms (eg, autonomic dysfunction, cognitive/neurobehavioral abnormalities, sleep disorders and sensory abnormalities such as anosmia, paresthesias and pain). Absence of rest tremor, early occurrence of gait difficulty, postural instability, dementia, hallucinations, and the presence of dysautonomia, ophthalmoparesis, ataxia and other atypical features, coupled with poor or no response to levodopa, suggest diagnoses other than PD. Conclusions: A thorough understanding of the broad spectrum of clinical manifestations of PD is essential to the proper diagnosis of the disease. Genetic mutations or variants, neuroimaging abnormalities and other tests are potential biomarkers that may improve diagnosis and allow the identification of persons at risk.

https://jnnp.bmj.com/content/jnnp/79/4/368.full.pdf

Parkinson’s disease: clinical features and diagnosis

Principles and Practice of Structural Equation Modeling (2nd ed.)

The authors conducted a content analysis on new scale development articles appearing in the Journal of Counseling Psychology during 10 years (1995 to 2004). The authors analyze and discuss characteristics of the exploratory and confirmatory factor analysis procedures in these scale development studies with respect to sample characteristics, factorability, extraction methods, rotation methods, item deletion or retention, factor retention, and model fit indexes. The authors uncovered a variety of specific practices that were at variance with the current literature on factor analysis or structural equation modeling. They make recommendations for best practices in scale development research in counseling psychology using exploratory and confirmatory factor analysis.

Scale Development Research: A Content Analysis and Recommendations for Best Practices

Measuring Health: A Guide to Rating Scales and Questionnaires

The purpose of this study was to use confirmatory factor analysis (CFA) to revise the factor structure of the CSAI-2 using one data set, and then to use CFA to validate the revised structure using a second data set. The first data set (calibration sample) consisted of 503 college-age intramural athletes, and the second (validation sample) consisted of 331 intercollegiate (Division I) and interscholastic athletes. The results of the initial CFA on the calibration sample resulted in a poor fit to the data. Using the Lagrange Multiplier Test (Gamma) as a guide, CSAI-2 items that loaded on more than one factor were sequentially deleted. The resulting 17-item revised CSAI-2 was then subjected to a CFA using the validation data sample. The results of this CFA revealed a good fit of the data to the model (CFI = .95, NNFI = .94, RMSEA = .054). It is suggested that the CSAI-2R instead of the CSAI-2 be used by researchers and practitioners for measuring competitive state anxiety in athletes.

Measuring Anxiety in Athletics: The Revised Competitive State Anxiety Inventory–2

Objective: Heavy alcohol use among college students represents a public health problem on American college campuses. A promising area for combating this problem is identifying protective behavioral strategies that may reduce consumption and its resulting negative consequences among students who do choose to use alcohol. The purpose of this study was to develop and conduct initial psychometric analyses on a new scale, which we named the Protective Behavioral Strategies Survey. Method: Data were collected on 437 undergraduate students, who volunteered to participate in the study, at a large, public university in the northeast region of the United States. Results: Results from an exploratory factor analysis yielded three theoretically meaningful factors that we labeled Limiting/Stopping Drinking, Manner of Drinking and Serious Harm Reduction. The three factors were, as a group, significantly associated with both alcohol consumption and alcohol-related problems, but the strongest unique relationship existed b...

Development of the Protective Behavioral Strategies Survey.

To determine the extent to which depression complicates Parkinson's disease (PD), the authors analyzed the literature on depression in PD in order to report on its prevalence, clinical manifestations, and treatment. By means of MEDLINE literature searches, the analysis focused on 45 PD depression studies conducted from 1922 through 1998. The results indicate that the prevalence of depression is 31% for all PD patients. The clinical manifestations of PD depression include apathy, psychomotor retardation, memory impairment, pessimism, irrationality, and suicidal ideation without suicidal behavior. PD depression is effectively treated with a variety of antidepressants, most commonly at present the selective serotonin reuptake inhibitors. Anecdotal evidence supports the use of sertraline to treat PD depression.

Prevalence, clinical manifestations, etiology, and treatment of depression in Parkinson's disease.

Structural equation modeling (SEM) has become increasingly popular for analyzing data in the social sciences, although several broad reviews of psychology journals suggest that many SEM researchers engage in questionable practices when using the technique. The purpose of this study is to review and critique the use of SEM in counseling psychology research regarding several of these questionable practices. One hundred five studies from 99 separate articles published in the Journal of Counseling Psychology between 1987 and 2003 were reviewed. Results of the review indicate that many counseling psychology studies do not engage in various best practices recommended by SEM experts (e.g., testing multiple a priori theoretical models or reporting all parameter estimates or effect sizes). Results also indicate that SEM practices in counseling psychology seem to be improving in some areas, whereas in other areas no improvements were noted over time. Implications of these results are discussed, and suggestions for ...

The Use of Structural Equation Modeling in Counseling Psychology Research

Researchers in the social norms area have previously focused primarily on alcohol consumption, paying comparatively less attention to drug use and sexual behavior. The major purposes of this study were to (1) compare perceptions of peer norms in the areas of alcohol use, drug use, and sexual behavior with actual behavior and (2) determine if a relationship existed between a student's perceptions of normative behavior and a student's actual behavior. Participants were 833 college students at a large, public university in the Northeast. Study participants overestimated alcohol use, drug use, and sexual behavior among their peers. There was also a positive relationship between actual behavior and perceived peer norms, although the effect sizes for all behaviors were small to moderate. The authors provide further support for the tenets of social norms theory and suggest that social norms interventions are appropriate both campus-wide and to targeted high-risk groups.

Matthew P. Martens

Papers

Measuring Anxiety in Athletics: The Revised Competitive State Anxiety Inventory–2

Development of the Protective Behavioral Strategies Survey.

Prevalence, clinical manifestations, etiology, and treatment of depression in Parkinson's disease.

The Use of Structural Equation Modeling in Counseling Psychology Research

Differences between actual and perceived student norms: an examination of alcohol use, drug use, and sexual behavior.