M
Matthieu Lestradet
Researcher at University of Strasbourg
Publications - 9
Citations - 129
Matthieu Lestradet is an academic researcher from University of Strasbourg. The author has contributed to research in topics: Apical cytoplasm & Gene. The author has an hindex of 6, co-authored 9 publications receiving 111 citations. Previous affiliations of Matthieu Lestradet include University of Burgundy & Centre national de la recherche scientifique.
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Journal ArticleDOI
Enterocyte Purge and Rapid Recovery Is a Resilience Reaction of the Gut Epithelium to Pore-Forming Toxin Attack
Kwang-Zin Lee,Matthieu Lestradet,Catherine Socha,Stefanie Schirmeier,Antonin Schmitz,Caroline Spenlé,Olivier Lefebvre,Céline Keime,Wennida Miriam Yamba,Richard Bou Aoun,Samuel Liégeois,Yannick Schwab,Patricia Simon-Assmann,Frédéric Dalle,Dominique Ferrandon +14 more
TL;DR: Two secreted peptides, the expression of which requires CyclinJ, that mediate the recovery phase in which enterocytes regain their original shape and volume are identified.
Journal ArticleDOI
The Drosophila ACP65A cuticle gene: deletion scanning analysis of cis-regulatory sequences and regulation by DHR38.
N. Bruey-Sedano,Josiane Alabouvette,Matthieu Lestradet,L. Hong,A. Girard,E. Gervasio,Brigitte Quennedey,Jean-Philippe Charles +7 more
TL;DR: The regulatory sequences of the Drosophila ACP65A cuticle gene were analyzed in vivo in transgenic flies, indicating the presence of tissue‐specific enhancers and response elements to hormone‐induced factors and the existence of independent hormonal and tissue‐ specific signaling pathways.
Journal ArticleDOI
A negative role for MyD88 in the resistance to starvation as revealed in an intestinal infection of Drosophila melanogaster with the Gram-positive bacterium Staphylococcus xylosus.
TL;DR: A novel function of MyD88 in the regulation of metabolism is uncovered that appears to be independent of its known roles in immunity and development, and is found to be more resistant to the ingestion of S. xylosus and to starvation than wild-type flies.
Journal ArticleDOI
Elucidation of the regulation of an adult cuticle gene Acp65A by the transcription factor Broad.
TL;DR: Broad (BR), an ecdysone‐inducible transcription factor, is a major determinant of the pupal stage and misexpression of BR‐Z1 during adult development of Drosophila melanogaster prevents the expression of the adult cuticle protein 65A gene (Acp65A).
Book ChapterDOI
Drosophila as a Model for Intestinal Infections
TL;DR: The methods that are currently in use to probe various aspects of the host-pathogen interactions between Drosophila and ingested microbes are presented, with an emphasis on the study of the midgut epithelium, which constitutes the major interface between the organism and the microbe-rich ingested food.