Maxim G. Vinogradov

TL;DR: In this review, recent applications of a stereoselective aza-Michael reaction as an efficient tool for the asymmetric synthesis of naturally occurring nitrogen-containing heterocyclic scaffolds and their usefulness to pharmacology are reviewed and summarized.

TL;DR: The Nazarov reaction (cyclization) is one of the most useful synthetic tools for the stereoselective preparation of various cyclopentenone scaffolds and recent applications are summarized.

TL;DR: In this article, the authors showed that the reaction proceeds by alkyne insertion into the metal-hydride bond of the intermediate (alkynyl)(hydride)Rh III complexes VII, VIII to give the (alklynyl)(vinyl) rh III species cis - (IX) and cis- (X) which were isolated.

TL;DR: In the presence of the chiral RuII-BINAP catalyst, the rate of hydrogenation of γ-ketoesters MeCOCH2CH2COOR (R = Et, Pri, But) greatly increases upon the addition of 5-10 equivalents of HCl with respect to ruthenium as discussed by the authors.

TL;DR: In this paper, a convenient one-step synthesis of chiral γ-lactones has been performed, based on enantioselective hydrogenation of γketoesters using the RuCl 3 -BINAP-HCl catalytic system.