M
Megan M. Moran
Researcher at Medical University of South Carolina
Publications - 3
Citations - 797
Megan M. Moran is an academic researcher from Medical University of South Carolina. The author has contributed to research in topics: Metabotropic glutamate receptor 2 & Nucleus accumbens. The author has an hindex of 3, co-authored 3 publications receiving 758 citations.
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Cystine/glutamate exchange regulates metabotropic glutamate receptor presynaptic inhibition of excitatory transmission and vulnerability to cocaine seeking.
TL;DR: It is demonstrated that nonsynaptic glutamate derived from xc- modulates synaptic glutamate release and thereby regulates cocaine-induced drug seeking.
Journal ArticleDOI
N-Acetylcysteine reverses cocaine-induced metaplasticity
Khaled Moussawi,Alejandra M. Pacchioni,Megan M. Moran,M. Foster Olive,Justin T. Gass,Antonieta Lavin,Peter W. Kalivas +6 more
TL;DR: It is shown that cocaine self-administration induces metaplasticity that inhibits further induction of synaptic plasticity, and this impairment can be reversed by NAC, a drug that also prevents relapse.
Journal ArticleDOI
Cystine/glutamate antiporter regulation of vesicular glutamate release.
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