M
Melanie J. Coathup
Researcher at University of Central Florida
Publications - 98
Citations - 2504
Melanie J. Coathup is an academic researcher from University of Central Florida. The author has contributed to research in topics: Osseointegration & Medicine. The author has an hindex of 22, co-authored 77 publications receiving 1816 citations. Previous affiliations of Melanie J. Coathup include University College London & Royal National Orthopaedic Hospital.
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Journal ArticleDOI
Osteoinduction of bone grafting materials for bone repair and regeneration.
TL;DR: The overall objective of this paper is to gather the current knowledge on osteoinductivity of bone grafting materials for the effective development of new graft substitutes that enhance bone regeneration.
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Demineralization–remineralization dynamics in teeth and bone
Ensanya A. Abou Neel,Anas Aljabo,Adam P Strange,Salwa Ibrahim,Melanie J. Coathup,Anne M. Young,Laurent Bozec,Vivek Mudera +7 more
TL;DR: Technologies discussed include composites with nano- and micron-sized inorganic minerals that can mimic mechanical properties of the tooth and bone in addition to promoting more natural repair of surrounding tissues.
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A comparison of bone remodelling around hydroxyapatite-coated, porous-coated and grit-blasted hip replacements retrieved at post-mortem
TL;DR: In this paper, the authors investigated the implant-bone interface around one design of femoral stem, proximally coated with either a plasma-sprayed porous coating (plain porous) or a hydroxyapatite porous surface (porous HA), or which had been grit-blasted (Interlok).
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The effects of microporosity on osteoinduction of calcium phosphate bone graft substitute biomaterials.
Oliver Chan,Oliver Chan,Melanie J. Coathup,A. Nesbitt,Chih-Yuan Ho,Karin A. Hing,Tom Buckland,Charlie Campion,Charlie Campion,Gordon Blunn +9 more
TL;DR: Bone formation and graft resorption had significantly increased in all groups so that the level of bone formation in the SiCaP-46 group had increased 75-fold to 30.05 ± 8.38%.
Journal ArticleDOI
Bone bonding to hydroxyapatite and titanium surfaces on femoral stems retrieved from human subjects at autopsy
Alexandra E. Porter,Punam Taak,Punam Taak,Linn W. Hobbs,Melanie J. Coathup,Gordon Blunn,Myron Spector +6 more
TL;DR: Many ultrastructural features of the bone bonded to the HA coatings on these implants from human subjects were comparable to those found on HA-coated devices implanted in a canine model.