M
Melanie M. Pearson
Researcher at University of Michigan
Publications - 33
Citations - 1618
Melanie M. Pearson is an academic researcher from University of Michigan. The author has contributed to research in topics: Proteus mirabilis & Gene. The author has an hindex of 18, co-authored 31 publications receiving 1301 citations. Previous affiliations of Melanie M. Pearson include New York University & Western Michigan University.
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Journal ArticleDOI
Proteus mirabilis and Urinary Tract Infections
TL;DR: The regulation of this complex process and its contribution to virulence is discussed, along with the type VI-secretion system-dependent intra-strain competition, which occurs during swarming.
Journal ArticleDOI
Complete Genome Sequence of Uropathogenic Proteus mirabilis, a Master of both Adherence and Motility
Melanie M. Pearson,Mohammed Sebaihia,Carol Churcher,Michael A. Quail,Aswin Sai Narain Seshasayee,Nicholas M. Luscombe,Zahra Abdellah,Claire Arrosmith,Becky Atkin,Tracey Chillingworth,Heidi Hauser,Kay Jagels,Sharon Moule,Karen Mungall,Halina Norbertczak,Ester Rabbinowitsch,Danielle Walker,Sally Whithead,Nicholas R. Thomson,Philip N. Rather,Julian Parkhill,Harry L. T. Mobley +21 more
TL;DR: The complete genome sequence of P. mirabilis HI4320 is reported, a representative strain cultured in the laboratory from the urine of a nursing home patient with a long-term (> or =30 days) indwelling urinary catheter.
Journal ArticleDOI
Pathogenesis of Proteus mirabilis Infection.
TL;DR: A comprehensive review of factors associated with urinary tract infection is presented, encompassing both historical perspectives and current advances.
Journal ArticleDOI
A hag mutant of Moraxella catarrhalis strain O35E is deficient in hemagglutination, autoagglutination, and immunoglobulin D-binding activities.
TL;DR: Results indicate that the surface-exposed Hag protein andUspA1 and UspA2 have the potential to interact both with each other and directly with host defense systems.
Journal ArticleDOI
Biofilm formation by Moraxella catarrhalis in vitro: roles of the UspA1 adhesin and the Hag hemagglutinin.
TL;DR: Transposon-mediated mutagenesis was used to identify Moraxella catarrhalis gene products necessary for biofilm development in a crystal violet-based assay involving 24-well tissue culture plates and revealed that the biofilm-positive transformant T14 contained a hybrid O46E-O35E uspA1 gene, with the N-terminal 155 amino acids being derived from the O 46E UspA1 protein.