Meng Ting Wang

TL;DR: New initiation of LABAs or LAMAs in patients with COPD is associated with an approximate 1.5-fold increased severe cardiovascular risk, irrespective of prior CVD status and history of exacerbations, whereas the risk was absent, or even reduced with prevalent use.

TL;DR: Statin use was associated with a reduced risk of COPD exacerbation, with a further risk reduction for statins prescribed more recently or at high doses, and for either short or long duration of statin use.

TL;DR: Compared to PTU, MMI/CBM are associated in a dose-dependent manner with an increased risk for hepatitis while the risks are similar for acute liver failure and cholestasis.

TL;DR: Antipsychotic use is associated with an acute and dose-dependent increased risk of ARF in patients with COPD, and Clinicians should exercise caution when prescribing antipsychotics to patientswith COPD and avoid high doses if possible.

TL;DR: There is empirical evidence that digoxin-diuretic interactions increased the risk of hospitalization for digoxin intoxication in HF patients, and the combined use of digoxin and diuretics should be avoided if possible.