M
Mengqian Li
Researcher at Sichuan University
Publications - 14
Citations - 408
Mengqian Li is an academic researcher from Sichuan University. The author has contributed to research in topics: Lung cancer & Tumor progression. The author has an hindex of 8, co-authored 11 publications receiving 230 citations.
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PD-1/PD-L1 Inhibitors in Cervical Cancer
TL;DR: The status and application of PD-1/PD-L1 inhibitors in clinical trials for the treatment of cervical cancer is summarized, some future directions in this field are suggested and some ongoing studies that may provide more evidence are suggested.
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Ionizing Radiation-Induced Cellular Senescence in Normal, Non-transformed Cells and the Involved DNA Damage Response: A Mini Review.
TL;DR: Senolytic agents, a class of small molecules that can selectively kill senescent cells, hold great potential to substantially reduce the side effects caused by radiotherapy while reasonably steer clear of carcinogenesis.
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Advancements and Obstacles of CRISPR-Cas9 Technology in Translational Research
TL;DR: This review summarizes developments and established preclinical applications of CRISPR-Cas9 technology, along with its current challenges, and highlights future applications in translational research.
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Effect of Low-Dose Radiation Therapy on Abscopal Responses to Hypofractionated Radiation Therapy and Anti-PD1 in Mice and Patients With Non-Small Cell Lung Cancer.
Limei Yin,Jianxin Xue,Rui Li,Lin Zhou,Lei Deng,Lin Chen,Yan Zhang,Yanying Li,Xuanwei Zhang,Weigang Xiu,Ruizhan Tong,Youling Gong,Meijuan Huang,Yong Xu,Jiang Zhu,Min Yu,Mengqian Li,Jie Lan,Jin Wang,Xianming Mo,Yuquan Wei,Gabriele Niedermann,You Lu +22 more
TL;DR: This study demonstrates preclinically that LDRT of established metastases significantly enhances the abscopal response to HFRT plus ICI, and shows that additional LDRt was well tolerated by patients, and this treatment profile is effective and worth further study.
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Immunosuppressive B cells expressing PD-1/PD-L1 in solid tumors: A mini review.
TL;DR: This review focuses on how B cells expressing PD-1/PD-L1 play immunosuppressive roles in tumor progression, aiming to figure out the potential for development of diagnostic tools and new therapies involving this unique group of cells.