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Xianming Mo
Researcher at Sichuan University
Publications - 100
Citations - 3183
Xianming Mo is an academic researcher from Sichuan University. The author has contributed to research in topics: Cancer & Zebrafish. The author has an hindex of 24, co-authored 89 publications receiving 2631 citations. Previous affiliations of Xianming Mo include Max Delbrück Center for Molecular Medicine.
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Journal ArticleDOI
RNA-directed gene editing specifically eradicates latent and prevents new HIV-1 infection
Wenhui Hu,Rafal Kaminski,Fan Yang,Yonggang Zhang,Laura Cosentino,Fang Li,Biao Luo,David Alvarez-Carbonell,Yoelvis García-Mesa,Jonathan Karn,Xianming Mo,Kamel Khalili +11 more
TL;DR: The results suggest that Cas9/gRNA can be engineered to provide a specific, efficacious prophylactic and therapeutic approach against AIDS.
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In Vivo Excision of HIV-1 Provirus by saCas9 and Multiplex Single-Guide RNAs in Animal Models.
Chaoran Yin,Ting Zhang,Xiying Qu,Yonggang Zhang,Raj Putatunda,Xiao Xiao,Fang Li,Weidong Xiao,Huaqing Zhao,Shen Dai,Xuebin Qin,Xianming Mo,Won Bin Young,Kamel Khalili,Wenhui Hu +14 more
TL;DR: In vivo excision of HIV-1 proviral DNA by sgRNAs/saCas9 in solid tissues/organs can be achieved via AAV delivery, a significant step toward human clinical trials.
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Ras Induces Mediator Complex Exchange on C/EBPβ
TL;DR: Results show that a Ras-induced structural alteration of C/EBPbeta determines differential gene activation through selective interaction with distinct Mediator complexes.
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Identification and expansion of cancer stem cells in tumor tissues and peripheral blood derived from gastric adenocarcinoma patients
Tie Chen,Kun Yang,Jian-Hua Yu,Wentong Meng,Dandan Yuan,Feng Bi,Fang Liu,Jie Liu,Bing Dai,Xin-Zu Chen,Fang Wang,Fan Zeng,Hong Xu,Jiankun Hu,Xianming Mo +14 more
TL;DR: The capture of GCSCs from the circulation of GAC patients shows great potential for identification of a critical cell population potentially responsible for tumor metastasis, and provides an effective protocol for early diagnosis and longitudinal monitoring of gastric cancer.
Journal ArticleDOI
Correlation between serum CA724 and gastric cancer: multiple analyses based on Chinese population
Xin-Zu Chen,Weike Zhang,Kun Yang,Lanlan Wang,Jin Liu,Li Wang,Jiankun Hu,Bo Zhang,Zhi-Xin Chen,Jia-Ping Chen,Zong-Guang Zhou,Xianming Mo +11 more
TL;DR: CA724 was the most correlative serum tumor biomarker for gastric cancer in Chinese population, and CA724+CEA+CA199 combination is considerable to improve sensitivity without impairing specificity.