M
Metaplasia Pikman
Publications - 1
Citations - 1161
Metaplasia Pikman is an academic researcher. The author has contributed to research in topics: Receptor & Thrombopoietin receptor. The author has an hindex of 1, co-authored 1 publications receiving 1092 citations.
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MPLW515L Is a Novel Somatic Activating Mutation in Myelofibrosis with Myeloid
Metaplasia Pikman,Benjamin H. Lee,Thomas Mercher,Elizabeth McDowell,Benjamin L. Ebert,Maricel Gozo,Adam Cuker,Gerlinde Wernig,Sandra A. Moore,Ilene Galinsky,Daniel J. DeAngelo,Jennifer J. Clark,Stephanie J. Lee,Todd R. Golub,Martha Wadleigh,D. Gary Gilliland,Ross L. Levine +16 more
TL;DR: Activation of JAK-STAT signaling via MPLW515L is an important pathogenetic event in patients with JAK2V617F-negative MF, including extramedullary hematopoiesis, splenomegaly, and megakaryocytic proliferation.