M
Michael D. Groaning
Researcher at Colorado State University
Publications - 11
Citations - 275
Michael D. Groaning is an academic researcher from Colorado State University. The author has contributed to research in topics: Bicyclic molecule & Lactam. The author has an hindex of 6, co-authored 11 publications receiving 267 citations.
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Journal ArticleDOI
Chiral Non-Racemic Bicyclic Lactams. Auxiliary-Based Asymmetric Reactions
Journal ArticleDOI
Allyldimethyltritylsilane. Synthesis of Cyclopentanols, Oxetanes, and Tetrahydrofurans by Reaction with Electron Deficient Olefins
TL;DR: In this article, an allyldimethyltritylsilane (ADTS) was employed to access a variety of cyclopentanols via Lewis acid mediated annulation to electron deficient olefins.
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Concise synthesis of indolizidines: total synthesis of (−)-coniceine
TL;DR: The Ti-mediated allylsilane addition to bicyclic lactams has been shown to have high stereoselectivity and combined with a ring closure method provides the title compounds in high energy efficiency.
Journal ArticleDOI
An asymmetric synthesis of the key precursor to (−)-indolizomycin
TL;DR: Using chiral bicyclic lactams, containing an α,β-unsaturation, the key precursor of (−)-indolizomycin was obtained in optically pure form as discussed by the authors.
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Allyldimethyltritylsilane: construction of enantiomerically pure cyclobutano[c]fused pyrrolidines
TL;DR: Cyclobutannulation of the bicyclic lactam with allyldimethyltritylsilane is accomplished in high yield with good diastereoselectivity as discussed by the authors.