M
Michael H. Norris
Researcher at University of Florida
Publications - 43
Citations - 802
Michael H. Norris is an academic researcher from University of Florida. The author has contributed to research in topics: Burkholderia pseudomallei & Melioidosis. The author has an hindex of 13, co-authored 38 publications receiving 586 citations. Previous affiliations of Michael H. Norris include Emerging Pathogens Institute & University of Hawaii at Manoa.
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Journal ArticleDOI
Transcript amplification from single bacterium for transcriptome analysis
Yun Kang,Michael H. Norris,Jan Zarzycki-Siek,William C. Nierman,Stuart P. Donachie,Tung T. Hoang +5 more
TL;DR: Data indicate that RNA-seq of TTA from a single cell is possible using this novel method and suggests that B. thailandensis, when exposed to the aromatic amino acid biosynthesis inhibitor glyphosate, induces (or represses) genes to possibly recuperate and balance the intracellular amino acid pool.
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Identification of antiviral antihistamines for COVID-19 repurposing.
Leah R. Reznikov,Michael H. Norris,Rohit Vashisht,Andrew P. Bluhm,Danmeng Li,Yan-Shin J. Liao,Ashley N. Brown,Atul J. Butte,David A. Ostrov +8 more
TL;DR: Diphenhydramine, hydroxyzine and azelastine are found to exhibit direct antiviral activity against SARS-CoV-2 in vitro.
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Multiple FadD acyl-CoA synthetases contribute to differential fatty acid degradation and virulence in Pseudomonas aeruginosa.
TL;DR: Ch Chromosomal mutagenesis, growth analysis, induction studies, and determination of kinetic parameters suggested that FadD1 has a substrate preference for long-chain FAs while fadD2 prefers shorter- Chain FAs, supporting the role of lipids as a significant nutrient source for this bacterium in vivo.
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Stable, site-specific fluorescent tagging constructs optimized for burkholderia species.
TL;DR: These vectors combined the effectiveness of the mini-Tn7 site-specific transposition system with fluorescent proteins optimized for Burkholderia spp.
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Glyphosate resistance as a novel select-agent-compliant, non-antibiotic-selectable marker in chromosomal mutagenesis of the essential genes asd and dapB of Burkholderia pseudomallei.
TL;DR: A selectable marker based on the gat gene, which confers resistance to the common herbicide glyphosate, is engineered to facilitate various genetic manipulations of Burkholderia select-agent species.