M
Michael H. Stewart
Researcher at United States Naval Research Laboratory
Publications - 89
Citations - 6906
Michael H. Stewart is an academic researcher from United States Naval Research Laboratory. The author has contributed to research in topics: Quantum dot & Förster resonance energy transfer. The author has an hindex of 36, co-authored 86 publications receiving 5975 citations. Previous affiliations of Michael H. Stewart include United States Department of the Navy & Los Alamos National Laboratory.
Papers
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Proceedings ArticleDOI
Further progress in cytosolic cellular delivery of quantum dots
Kelly Boeneman Gemmill,James B. Delehanty,Michael H. Stewart,Kimihiro Susumu,Juan B. Blanco-Canosa,Philip E. Dawson,Alan L. Huston,Igor L. Medintz +7 more
TL;DR: Palm-1, a palmitylated peptide that is capable of both cellular uptake and rapid endosomal escape in multiple cell lines without concomitant toxicity, is shown to be the superior method for cytosolic delivery of QDs.
Proceedings ArticleDOI
Enhancing enzymatic efficiency by attachment to semiconductor nanoparticles for biosensor applications
Joyce C. Breger,Joyce C. Breger,Scott A. Walper,Eunkeu Oh,Kimihiro Susumu,Michael H. Stewart,Jeffrey R. Deschamps,Mario G. Ancona,Igor L. Medintz +8 more
TL;DR: Enhanced enzyme performance for the neutralization of a simulant nerve agent when attached to two distinctly-sized QDs is most likely due to increased enzyme-substrate interactions from improvements in enzyme orientation, enzyme density, and substrate diffusion on or near the QD.
Patent
Fabrication of Luminescent Quantum Dot Thiol-yne Nanocomposites With Tailorable Optical, Thermal and Mechanical Properties
TL;DR: In this article, a method of making a ligand for Quantum Dot functionalization, and a functionalized Quantum Dot (QD) with ligand, was described, which can be used in additive manufacturing.
Patent
Multifunctional nanoparticle bioconjugates for photoacoustic-based recording of cellular membrane potential
James B. Delehanty,Michael H. Stewart,Nag Okhil,Jeffrey R. Deschamps,Kimihiro Susumu,Eunkeu Oh,Lauren D. Field,Alexander L. Efros,Alan L. Huston,Igor L. Medintz,Philip E. Dawson,Nashaat Rasheed,Parag V. Chitnis,John R. Cressman +13 more
TL;DR: In this paper, a construct for detecting cellular membrane potential includes a nanoparticle operable as an electron donor, a modular peptide attached to the nanoparticle, the peptide comprising a nanoparticles association domain, a motif configured to mediate peptide insertion into the plasma membrane, and at least one attachment point for an electron acceptor positioned at a controlled distance from the nanoparticles.
Enhanced Kinetics of Enzymatic Nanosensors
Mario G. Ancona,Joyce C. Breger,Igor L. Medintz,Michael H. Stewart,Kimihiro Susumu,Scott A. Walper +5 more
TL;DR: An engineered enzyme construct’s effectiveness when attached to QDs is analyzed illustrating an important biological threat application: neutralization of paraoxon, a simulant nerve agent.