M
Michael H. Stewart
Researcher at United States Naval Research Laboratory
Publications - 89
Citations - 6906
Michael H. Stewart is an academic researcher from United States Naval Research Laboratory. The author has contributed to research in topics: Quantum dot & Förster resonance energy transfer. The author has an hindex of 36, co-authored 86 publications receiving 5975 citations. Previous affiliations of Michael H. Stewart include United States Department of the Navy & Los Alamos National Laboratory.
Papers
More filters
Journal ArticleDOI
Quantum-dot/dopamine bioconjugates function as redox coupled assemblies for in vitro and intracellular pH sensing.
Igor L. Medintz,Michael H. Stewart,Scott A. Trammell,Kimihiro Susumu,James B. Delehanty,Bing C. Mei,Bing C. Mei,Joseph S. Melinger,Juan B. Blanco-Canosa,Philip E. Dawson,Hedi Mattoussi +10 more
TL;DR: It is demonstrated that QD-dopamine-peptide bioconjugates can function as charge-transfer coupled pH sensors and a detailed mechanism describing the QD quenching processes that is consistent with dopamine's inherent redox chemistry is presented.
Journal ArticleDOI
Quantum Dots as Simultaneous Acceptors and Donors in Time-Gated Förster Resonance Energy Transfer Relays: Characterization and Biosensing
W. Russ Algar,David K. Wegner,Alan L. Huston,Juan B. Blanco-Canosa,Michael H. Stewart,Anika Armstrong,Philip E. Dawson,Niko Hildebrandt,Igor L. Medintz +8 more
TL;DR: The utility of incorporating QDs into this type of time-gated energy transfer configuration was demonstrated in prototypical bioassays for monitoring protease activity and nucleic acid hybridization; the latter included a dual target format where each orthogonal FRET step transduced a separate binding event.
Journal ArticleDOI
Multidentate Poly(ethylene glycol) Ligands Provide Colloidal Stability to Semiconductor and Metallic Nanocrystals in Extreme Conditions
Michael H. Stewart,Kimihiro Susumu,Bing C. Mei,Igor L. Medintz,James B. Delehanty,Juan B. Blanco-Canosa,Philip E. Dawson,Hedi Mattoussi +7 more
TL;DR: The improved colloidal stability of nanocrystals afforded by the tetradentate ligands was further demonstrated via the assembly of stable QD-nuclear localization signal peptide bioconjugates that promoted intracellular uptake.
Journal ArticleDOI
Quantum dot peptide biosensors for monitoring caspase 3 proteolysis and calcium ions.
Duane E. Prasuhn,Anne Feltz,Juan B. Blanco-Canosa,Kimihiro Susumu,Michael H. Stewart,Bing C. Mei,Aleksey V. Yakovlev,Christina Loukov,Jean-Maurice Mallet,Martin Oheim,Philip E. Dawson,Igor L. Medintz +11 more
TL;DR: This report functionalize QDs with dye-labeled peptides using two different linkage chemistries to yield Förster resonance energy transfer (FRET)-based sensors capable of monitoring either enzymatic activity or ionic presence.
Journal ArticleDOI
Quantum dot DNA bioconjugates: attachment chemistry strongly influences the resulting composite architecture.
Kelly Boeneman,Jeffrey R. Deschamps,Susan Buckhout-White,Duane E. Prasuhn,Juan B. Blanco-Canosa,Philip E. Dawson,Michael H. Stewart,Kimihiro Susumu,Ellen R. Goldman,Mario G. Ancona,Igor L. Medintz +10 more
TL;DR: The architecture that results from using two common self-assembly chemistries to attach DNA to QDs is compared to suggest that if a particular QD biocomposite structure is desired, for example, random versus oriented, the type of bioconjugation chemistry utilized will be a key influencing factor.