Michael Holmes

TL;DR: There is evidence to suggest that statin therapy is associated with a statistically significant reduction in the risk of primary and secondary cardiovascular events and there is limited evidence for the effectiveness of statins in different subgroups.

TL;DR: The Fifth Mount Hood Challenge allowed modelers to identify important differences between models, address key methodological challenges, and discuss avenues of research to improve future diabetes models.

TL;DR: The evidence suggested that SCS was effective in reducing the chronic neuropathic pain of FBSS and CRPS type I and in delaying refractory angina pain onset during exercise at short-term follow-up.

TL;DR: In this paper, a systematic review of the literature sought clinical and cost-effectiveness data for SCS in adults with chronic neuropathic or ischaemic pain with inadequate response to medical or surgical treatment other than SCS.

TL;DR: Evaluated the clinical and cost-effectiveness of machine perfusion compared to cold storage, as a means of preserving kidneys prior to transplantation, indicated that in the long-term MP would be expected to be cheaper and more effective than CS for both HBD and NHBD recipients.