M
Michael J. Hynes
Researcher at National University of Ireland, Galway
Publications - 266
Citations - 11221
Michael J. Hynes is an academic researcher from National University of Ireland, Galway. The author has contributed to research in topics: Aspergillus nidulans & Gene. The author has an hindex of 55, co-authored 265 publications receiving 10695 citations. Previous affiliations of Michael J. Hynes include University of Melbourne & National University of Ireland.
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Differential expression of Aspergillus nidulans ammonium permease genes is regulated by GATA transcription factor AreA.
TL;DR: It is shown that meaA is expressed in the presence of ammonium, consistent with the function of MeaA as the main ammonium transporter required for optimal growth on ammonium as a nitrogen source.
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Deletion and overexpression of the Aspergillus nidulans GATA factor AreB reveals unexpected pleiotropy
TL;DR: It is shown that AreB negatively regulates AreA-dependent nitrogen catabolic gene expression under nitrogen-limiting or nitrogen-starvation conditions and deletion of either the DNA-binding domain or the leucine zipper domain results in loss of both nitrogen and developmental phenotypes.
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Genetic transformation of filamentous fungi
TL;DR: Many filamentous fungi of all taxa can now be subject to DNA-mediated transformation and the range available is increasing as new genes are cloned, allowing investigation of many problems in fungi with good genetic systems.
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The tamA gene of Aspergillus nidulans contains a putative zinc cluster motif which is not required for gene function.
TL;DR: The tamA gene is cloned by complementation of a new tamA allele and it is indicated that in vitro mutagenesis of sequences encoding a putative zinc cluster DNA binding domain indicated that this motif is not required for in vivo TamA function.