M
Michael J. Sorich
Researcher at Flinders University
Publications - 184
Citations - 5157
Michael J. Sorich is an academic researcher from Flinders University. The author has contributed to research in topics: Medicine & Atezolizumab. The author has an hindex of 32, co-authored 163 publications receiving 3963 citations. Previous affiliations of Michael J. Sorich include Sewanee: The University of the South & University of South Australia.
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Extended RAS mutations and anti-EGFR monoclonal antibody survival benefit in metastatic colorectal cancer: a meta-analysis of randomized, controlled trials
Michael J. Sorich,Michael D. Wiese,Andrew Rowland,Ganessan Kichenadasse,Ross A. McKinnon,Christos S. Karapetis +5 more
TL;DR: Tumors harboring one of the new RAS mutations are unlikely to significantly benefit from anti-EGFR mAb therapy in mCRC, and results were consistent between different anti- EGFR agents, lines of therapy and chemotherapy partners.
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Low relative abundances of the mucolytic bacterium Akkermansia muciniphila and Bifidobacterium spp. in feces of children with autism.
Lv Wang,Claus T. Christophersen,Michael J. Sorich,Jacobus P. Gerber,Manya Angley,Michael A. Conlon +5 more
TL;DR: Lower relative abundances of Bifidobacteria species and the mucolytic bacterium Akkermansia muciniphila were found in children with autism, the latter suggesting mucus barrier changes.
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Increased abundance of Sutterella spp. and Ruminococcus torques in feces of children with autism spectrum disorder
Lv Wang,Claus T. Christophersen,Michael J. Sorich,Jacobus P. Gerber,Manya Angley,Michael A. Conlon +5 more
TL;DR: Further evidence of changes in the gut microbiota of children with ASD is shown and it is confirmed that the abundance of Sutterella spp.
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Elevated Fecal Short Chain Fatty Acid and Ammonia Concentrations in Children with Autism Spectrum Disorder
Lv Wang,Claus T. Christophersen,Michael J. Sorich,Jacobus P. Gerber,Manya Angley,Michael A. Conlon +5 more
TL;DR: The results suggest fermentation processes or utilization of fermentation products may be altered in children with ASD compared to children without ASD.
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Meta-analysis of BRAF mutation as a predictive biomarker of benefit from anti-EGFR monoclonal antibody therapy for RAS wild-type metastatic colorectal cancer.
Andrew Rowland,Mafalda M. Dias,Michael D. Wiese,Ganessan Kichenadasse,Ross A. McKinnon,Christos S. Karapetis,Michael J. Sorich +6 more
TL;DR: It is demonstrated that there is insufficient evidence to definitively state that RAS WT/BRAF MT individuals attain a different treatment benefit from anti-EGFR mAbs for mCRC compared with RASWT/B RAF WT individuals, and there are insufficient data to justify the exclusion of anti- EGFR mAb therapy for patients with MCRC.