M
Michael Koch
Researcher at Wellcome Trust
Publications - 1
Citations - 254
Michael Koch is an academic researcher from Wellcome Trust. The author has contributed to research in topics: Epitope & T cell. The author has an hindex of 1, co-authored 1 publications receiving 243 citations.
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T Cell Responses in Dengue Hemorrhagic Fever: Are Cross-Reactive T Cells Suboptimal?
Juthathip Mongkolsapaya,Thaneeya Duangchinda,Wanwisa Dejnirattisai,Sirijit Vasanawathana,Panisadee Avirutnan,Aroonroong Jairungsri,Nuanpan Khemnu,Nattaya Tangthawornchaikul,P Chotiyarnwong,Kanokwan Sae-Jang,Michael Koch,Yvonne Jones,Andrew J. McMichael,Xiao-Ning Xu,Prida Malasit,Prida Malasit,Gavin R. Screaton +16 more
TL;DR: A T cell epitope restricted by HLA-A*24, a major MHC class I allele, in Southeast Asia is examined in a cohort of children admitted to a hospital with acute Dengue infection, and the cytokine profiles and the degranulation capacity of T cells generated to this epitope are defined and compared across different viral serotypes.