M
Michael M. Kim
Researcher at Oregon Health & Science University
Publications - 19
Citations - 1204
Michael M. Kim is an academic researcher from Oregon Health & Science University. The author has contributed to research in topics: Head and neck squamous-cell carcinoma & Cancer. The author has an hindex of 14, co-authored 19 publications receiving 1109 citations. Previous affiliations of Michael M. Kim include Johns Hopkins University & Johns Hopkins University School of Medicine.
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Journal ArticleDOI
Evaluation of promoter hypermethylation detection in body fluids as a screening/diagnosis tool for head and neck squamous cell carcinoma
André Lopes Carvalho,Carmen Jerónimo,Michael M. Kim,Rui Henrique,Zhe Zhang,Mohammad O. Hoque,Steve Chang,Mariana Brait,Chetan S. Nayak,Wei Wen Jiang,Quia Claybourne,Yutaka Tokumaru,Juna Lee,David M. Goldenberg,Elizabeth Garrett-Mayer,Steven D. Goodman,Chul So Moon,Wayne M. Koch,William H. Westra,David Sidransky,Joseph A. Califano +20 more
TL;DR: Q-MSP detection of HNSCC in serum and salivary rinses using multiple targets offers improved performance when compared with single markers, and compartment-specific methylation in normal subjects affects the utility of Q-M SP detection strategies.
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Mitochondrial DNA quantity increases with histopathologic grade in premalignant and malignant head and neck lesions.
Michael M. Kim,John D. Clinger,Brett G. Masayesva,Patrick K. Ha,Marianna Zahurak,William H. Westra,Joseph A. Califano +6 more
TL;DR: This study shows that mtDNA increases according to histopathologic grade, a phenomenon that may be a feedback mechanism that compensates for a generalized decline in respiratory chain function, Therefore, high mtDNA content may be another marker of genetic alteration, a measure of relative DNA injury, and a surrogate measure of histopathological grade.
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Molecular pathology of head-and-neck cancer.
TL;DR: Improved molecular characterization of primary tumors, surgical margins and body fluids may allow clinicians to detect and treat earlier lesions, predict a tumor's response to treatment, tailor treatment to specific molecular alterations and ultimately improve clinical outcomes related to HNSC.
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Habitual risk factors for head and neck cancer.
David M. Goldenberg,Juna Lee,Wayne M. Koch,Michael M. Kim,Barry Trink,David Sidransky,Chul So Moon +6 more
TL;DR: Habitual and social risk factors for cancer of the head and neck, excluding smoking and alcohol consumption are reviewed.
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Use of customized polyetheretherketone (PEEK) implants in the reconstruction of complex maxillofacial defects.
TL;DR: This work describes a series of 4 patients whose defects were reconstructed using customized PEEK implants that had excellent postoperative aesthetic and functional results without complications such as infections or extrusions.