M
Michael Nöldner
Publications - 44
Citations - 754
Michael Nöldner is an academic researcher. The author has contributed to research in topics: Hyperforin & Hypericum perforatum. The author has an hindex of 12, co-authored 44 publications receiving 727 citations.
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Journal ArticleDOI
Antidepressant Activity of Hypericum Perforatum and Hyperforin: the Neglected Possibility
TL;DR: The observations made during this study indicate that hyperforin is the major, but not the only antidepressive component of alcoholic extracts.
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Damaged neuronal energy metabolism and behavior are improved by Ginkgo biloba extract (EGb 761).
TL;DR: The ongoing deterioration in behavior and the maintained deficit in cerebral energy metabolism occurring after a triplicate icv streptozotocin (STZ) injection were significantly slowed down by EGb761, underscoring the beneficial effect of EGb 761 that had been reported in dementia disorders.
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Microstructured scaffolds for liver tissue cultures of high cell density: morphological and biochemical characterization of tissue aggregates.
Erik Eschbach,Shyam Sunder Chatterjee,Michael Nöldner,Eric Gottwald,Hermann Dertinger,Karl-Friedrich Weibezahn,Gudrun Knedlitschek +6 more
TL;DR: The described culture efficiently supports liver‐specific functions of adult rat hepatocytes and seems to be suited not only for use in an extracorporeal liver device but also for the formation of evenly sized small aggregates to be of use in transplantation of differentiated liver tissue.
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Hypericum extract and hyperforin: memory-enhancing properties in rodents.
TL;DR: The observations suggest that the Hypericum extract could be a novel type of antidepressant with memory enhancing properties, and indicate that hyperforin is involved in its cognitive effects.
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Hyperforin attenuates various ionic conductance mechanisms in the isolated hippocampal neurons of rat
Shyam Sunder Chatterjee,V. M. Filippov,Polina V. Lishko,Oleksandr Maximyuk,Michael Nöldner,Oleg Krishtal +5 more
TL;DR: It is reconfirm that hyperforin is a major neuroactive component of hypericum extracts but also demonstrate that this structurally unique and naturally abundant molecule is a potent modulation of mechanism involved in the control of neuronal ionic conductances.